The role of project management in the implementation of projects in science financed from EU programs depends on the knowledge and experience of the project manager, and then of the entire project team, as well as their willingness and efforts to successfully implement such projects. Usually, such projects are carried out at the international level or in cooperation with other partner universities, and have specific project goals that affirm a series of project results with the product of scientific innovation. Therefore, the application of project management in scientific projects is very important, and the role of the EU program in such projects is most pronounced from the financial side, with the contribution of potential international cooperation and assistance to the limited budget of the scientific institution. Today, numerous projects in Croatian science are financed from EU programs, which represents a number of useful advantages for such projects. Namely, these are projects that are mainly implemented by universities and where the project managers are mostly university professors with extensive work experience, because such a project is expected to result in some new scientific knowledge and achievement that has not been achieved in science so far. The availability of EU programs for financing such projects provides generous financial resources to Universities and relieves them of personal investments that burden the budgets of such educational institutions and sometimes call into question the potential of their implementation.