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undergraduate thesis
Simulacija DNA sljedova korištenjem Gillespiejevog algoritma
Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing, 2024. urn:nbn:hr:168:136976
Topolko, Lucija
University of Zagreb
Faculty of Electrical Engineering and Computing

Institutional repository: FER Repository

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Topolko, L. (2024). Simulacija DNA sljedova korištenjem Gillespiejevog algoritma (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing. Retrieved from https://urn.nsk.hr/urn:nbn:hr:168:136976

Topolko, Lucija. "Simulacija DNA sljedova korištenjem Gillespiejevog algoritma." Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2024. https://urn.nsk.hr/urn:nbn:hr:168:136976

Topolko, Lucija. "Simulacija DNA sljedova korištenjem Gillespiejevog algoritma." Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2024. https://urn.nsk.hr/urn:nbn:hr:168:136976

Topolko, L. (2024). 'Simulacija DNA sljedova korištenjem Gillespiejevog algoritma', Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, accessed 30 November 2024, https://urn.nsk.hr/urn:nbn:hr:168:136976

Topolko L. Simulacija DNA sljedova korištenjem Gillespiejevog algoritma [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing; 2024 [cited 2024 November 30] Available at: https://urn.nsk.hr/urn:nbn:hr:168:136976

L. Topolko, "Simulacija DNA sljedova korištenjem Gillespiejevog algoritma", Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:168:136976

Metadata
TitleSimulacija DNA sljedova korištenjem Gillespiejevog algoritma
Title (english)DNA sequence simulation based on Gillespie algorithm
AuthorLucija Topolko
MentorMirjana Domazet-Lošo (mentor)
Committee memberMirjana Domazet-Lošo (predsjednik povjerenstva)
Committee memberMihael Kovač (član povjerenstva)
Committee memberAndrej Slapničar (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Electrical Engineering and Computing
Zagreb
Defense date and country2024-06-27, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Computing
Abstract
Simulatori DNA sljedova ključni su alati u molekularnoj biologiji i bioinformatičkom istraživanju jer omogućuju simuliranje kompleksnih evolucijskih procesa kroz generacije. Ovi alati su od velikog značaja za istraživanje genetičke varijabilnosti, evolucijskih trendova i adaptivnih strategija organizama. U ovom radu razvijen je simulator temeljen na Gillespiejevom algoritmu. Gillespiejev algoritam predstavlja matematičku metodu za simulaciju stohastičkih procesa u biološkim sustavima. Ovaj simulator omogućava simulaciju DNA sljedova koristeći Jukes-Cantorov i Kimurin evolucijski model. Implementiran je u programskom jeziku C++, a testiran je na podacima virusa HIV-1. Rezultati su uspoređeni s rezultatima alata AliSim kako bi se provjerila njegova učinkovitost i pouzdanost.
Abstract (english)
DNA sequence simulators are key tools in molecular biology and bioinformatics research, as they enable the simulation of complex evolutionary processes across generations. These tools hold significant importance for studying genetic variability, evolutionary trends, and adaptive strategies of organisms. In this study, a simulator based on the Gillespie algorithm was developed. The Gillespie algorithm is a mathematical method for simulating stochastic processes in biological systems. This simulator allows for the simulation of DNA sequences using the Jukes-Cantor and Kimura evolutionary models. It was implemented in the programming language C++ and tested using HIV-1 virus data. The results were compared with those of the AliSim tool to verify its effectiveness and reliability.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:168:136976
Study programmeTitle: Computing
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka računarstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka računarstva)
Type of resourceText
File originBorn digital
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Created on2024-10-12 22:21:34