The aim of this study is to examine some of the correlates of the sexual quality of life in women diagnosed with breast cancer, including sociodemographic and clinical determinants. The study also addresses adaptive and maladaptive coping strategies within the population. The research was conducted on a convenience sample via an online survey. A total of 228 women participated, with an average age of 50.7 years. The instruments used included the Sexual Quality of Life Questionnaire-Female (SQOL-F), the Female Sexual Function Index (FSFI), the Relationship Assessment Scale (RAS), and the Coping Inventory for Stressful Situations (CISS), along with an assessment of some sociodemographic characteristics of the participants. The results indicated that women who did not undergo mastectomy reported a better sexual quality of life, as did those who were not yet in menopause. Generally, the FSFI results suggest the presence of sexual dysfunction. The quality of romantic relationships did not show a significant correlation with the quality of sexual functioning. Task-oriented and avoidance coping strategies were positively correlated with the quality of sexual life, while emotion-oriented coping strategies showed the opposite relationship. Older women and those with higher socioeconomic status also reported higher levels of sexual functioning quality.