In this thesis the preparation of 4-Bromo-1,8-Naphthalic anhydride derivatives was described which included nucleophilic aromatic substitution and addition-elimination reactions of naphthalic anhydride derivative with selected aniline derivatives. The reaction of nucleophilic aromatic substitution on the starting compound, 4-Bromo-1,8-Naphthalic anhydride resulted with the preparation of an azide derivative, compound 1 which was used as a starting compound in the second reaction step that involved addition-elimination reaction with the selected aniline derivatives. With the aim of investigation of influence electron-acceptor and electron-donor groups on the reaction yield, as starting aniline derivatives para-phenylenediamine and para-nitroaniline were chosen. Only the amino derivative, compound 2 was prepared using the proposed synthetic route, while for the synthesis of compound A two synthetic pathways were proposed. Method i) which is identical to methode used to prepare compound 2 and method ii) which implies another synthetic route. To investigate the use of compound 2 as an indicator for intracellular H2S, compound 2 was tried to be reduced with an excess H2S. The reduction was carried out successfully which was assumed by comparing the solutions of reduced and non-reduced forms of compound 2 under UV lamp (365 nm). Structures of compounds 1 and 2 were assumed by 1H and 13C NMR spectroscopy.