The anterior cruciate ligament is important in maintaining knee stability and proper kinematics of the knee. In high-performance athletes, the anterior cruciate ligament is the most commonly disrupted ligament in the knee. Female athletes due to landing technique and leg alignment have a higher risk for this injury. A significant proportion of these injuries are caused by non-contact mechanisms, therefore, jump-training-type prevention programs are effective at reducing the incidence of these injuries, especially when instituted early in the development of the athlete. Most patients undergo the reconstruction of the ligament, after which rehabilitation was started. The operation is often delayed to perform preoperative rehabilitation, which is the same as the initial part of nonoperative treatment. The goal of this approach is to reduce swelling, inflammation and pain, and restore normal range of movement, normalize walking and prevent muscular atrophy before surgery. Patients undergoing preoperative rehabilitation progress faster in postoperative rehabilitation. After injury and surgery, inhibition of quadriceps is common due to pain and inflammation, therefore, it is extremely important to reduce the effusion with cryotherapy, compression, and elevation. Kinesitherapy is the basic method used to rehabilitate patients with anterior cross ligament injury. Current approaches to ACL rehabilitation emphasize the importance of immediate motion, early weight bearing, immediate muscle exercises, closed kinetic chain exercises, early functional activities, and earlier return to sports. Immediately after injury or reconstruction, the complete passive extension of the knee should be restored, while flexion is gradually returned. Also, the volunteer control of the quadriceps activation should start immediately. It is important to strengthen other muscles such as hamstring, hip, trunk and calf muscles. Current rehabilitation programs focus not only on strengthening exercises but also on the training of proprioception and neuromuscular control to provide neurological stimulus and consequently dynamically strengthen and stabilise the knee. Each patient is different therefore the duration of rehabilitation cannot be the same for everyone. With regard to the associated injuries, the type of transplant and gender, the rehabilitation process needs to be adjusted. Rehabilitation progression is based on meeting the clinical goals of a particular phase rather than time frames. Constantly increasing pain and effusion during the rehabilitation program are a sign of pre-aggressive approach.