Rheumatoid arthritis is a systemic inflammatory disease primarily affecting joints. It is a significant cause of decreased quality of life and life expectancy. It affects mostly women, the ratio women to men being 3:1. About 0.8 – 1% of European population is affected. There are various kinds of therapy, including pharmacological, nonpharmacological – physical and occupational therapy and special exercises – and surgical therapy. Physical activity (PA) should be implemented in patients' lives as a part of the nonpharmacological therapy, but there is a problem regarding a vast number of doctors and patients not being aware of the benefits of PA. The guidelines for PA for health maintenance in general population were published in 2011 by WHO and in 2018 by ACSM. A small number of patients diagnosed with RA is informed about the guidelines and performs PA according to the guidelines. Nevertheless, a great number of patients is physically inactive. Another problem is the guidelines being not specific for rheumatoid arthritis patients, as they are written for the healthy adult population. New guidelines were recently published (in 2018) specifically for the inflammatory arthritis and osteoarthritis patients and these guidelines emphasize that PA should be a mandatory part of care in these patients and that therapeutic PA should include aerobic PA, muscle strengthening exercises, flexibility exercises and neuromuscle training of balance and walking. The effects od PA are dependable on the dose and duration of PA, therefore it is necessary to include behavioral techniques to improve long-term adherence to PA. There are numerous benefits of regular PA of certain intensity that can be accomplished in the patients with RA: PA decreases the risk for RA development, it decreases disease activity level in RA patients, improves musculoskeletal status and joint status, improves functional status and, finally, improves quality of life, which is decreased in these patients. Other benefits of PA in RA can be seen in cardiovascular system, glycemia and bodyweight regulation, mental health, decreased incidence of malignant diseases and decreased all-cause mortality.