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master's thesis
Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije
Zagreb: University of Zagreb, School of Medicine, 2021. urn:nbn:hr:105:008840
Šenjug, Maks Luka
University of Zagreb
School of Medicine
Department of Pathophysiology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Šenjug, M. L. (2021). Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:008840

Šenjug, Maks Luka. "Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije." Master's thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:008840

Šenjug, Maks Luka. "Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije." Master's thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:008840

Šenjug, M. L. (2021). 'Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije', Master's thesis, University of Zagreb, School of Medicine, accessed 19 April 2024, https://urn.nsk.hr/urn:nbn:hr:105:008840

Šenjug ML. Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2021 [cited 2024 April 19] Available at: https://urn.nsk.hr/urn:nbn:hr:105:008840

M. L. Šenjug, "Doprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:105:008840

Metadata
TitleDoprinos smanjenog unosa kalija u etiopatogenezi arterijske hipertenzije
Title (english)Contribution of reduced potassium intake in the etiopathogenesis of arterial hypertension
AuthorMaks Luka Šenjug
MentorZdenko Kovač (mentor)
Committee memberMaja Sirotković Skerlev (predsjednik povjerenstva)
Committee memberJasenka Markeljević (član povjerenstva)
Committee memberZdenko Kovač (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Pathophysiology)
Zagreb
Defense date and country2021-09-25, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathophysiology
Abstract
Arterijska hipertenzija jedna je od najčešćih kroničnih bolesti, posljedica koje je veliko opterećenje zdravstvenih sustava diljem svijeta. Hipertenzija je multifaktorijalna bolest za koju su faktori rizika genetsko naslijeđe, okolišni čimbenici i rizična ponašanja. Uzrok hipertenzije najčešće se ne može otkriti (primarna hipertenzija), stoga se i dalje intenzivno istražuju načini kojima organizam održava krvni tlak. Lijekovi za liječenje hipertenzije smanjuju krvni tlak povećanjem gubitka vode i soli putem bubrega, širenjem krvnih žila ili usporavanjem srčanog rada. Opservacijska istraživanja su dugo pokazivala vezu između manje učestalosti hipertenzije i povećanog unosa kalija prehranom. U novije vrijeme su se počeli razmatrati i paleoantropološki dokazi o znatno većem unosu kalija u razdoblju prije razvoja poljoprivrede i prehrambene industrije. Osim smanjenog unosa kalija, današnja prehrana opterećena je i velikim unosom natrija (kuhinjska sol). Suvremena istraživanja, koja uključuju in vivo i randomizirane kliničke studije, pokazuju pozitivan učinak povećanja unosa kalija na visoki krvni tlak. Povećanje unosa kalija povećava gubitak soli i vode putem bubrega djelovanjem na prijenosnike za natrij i kalij.
Abstract (english)
Arterial hypertension is one of the most common non-communicable diseases, a source of a great number of healthcare expenses across the world. Hypertension is a multifactorial disease involving genetic and environmental risk factors and behavioural risks. Causes of hypertension are mostly unknown (primary hypertension) and therefore intensive research of blood pressure control mechanisms continues. Medications for treating hypertension reduce blood pressure by increasing salt and water loss through the kidneys, dilating blood vessels, or decreasing cardiac output. Observational studies have long been signalling a link between a lower incidence of hypertension and an increased intake of potassium in the diet. Recently research has started into paleoanthropological data regarding greater intake of potassium before the development of agriculture and food industry. Besides the reduced intake of potassium, the modern diet is very high in sodium (table salt). Current research, including in vivo and randomized clinical studies, show a beneficial effect of increased potassium intake on high blood pressure. Increasing potassium intake leads to an increase in salt and water loss through the kidneys by influencing sodium and potassium transporters.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:008840
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-05-12 08:46:35