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master's thesis
Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen
Zagreb: University of Zagreb, Faculty of Agriculture, 2019. urn:nbn:hr:204:220852
Popijač, Vedrana
University of Zagreb
Faculty of Agriculture
Animal Science

Institutional repository: Repository Faculty of Agriculture University of Zagreb

Cite this document

Popijač, V. (2019). Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen (Master's thesis). Zagreb: University of Zagreb, Faculty of Agriculture. Retrieved from https://urn.nsk.hr/urn:nbn:hr:204:220852

Popijač, Vedrana. "Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen." Master's thesis, University of Zagreb, Faculty of Agriculture, 2019. https://urn.nsk.hr/urn:nbn:hr:204:220852

Popijač, Vedrana. "Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen." Master's thesis, University of Zagreb, Faculty of Agriculture, 2019. https://urn.nsk.hr/urn:nbn:hr:204:220852

Popijač, V. (2019). 'Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen', Master's thesis, University of Zagreb, Faculty of Agriculture, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:204:220852

Popijač V. Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen [Master's thesis]. Zagreb: University of Zagreb, Faculty of Agriculture; 2019 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:204:220852

V. Popijač, "Utjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen", Master's thesis, University of Zagreb, Faculty of Agriculture, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:204:220852

Metadata
TitleUtjecaj štetnih mutacija u uzgoju mliječnih goveda s osvrtom na APAF1 gen
Title (english)Influence of harmful mutations in dairy cattle with a review to APAF1 gen
AuthorVedrana Popijač
MentorVlatka Čubrić Čurik (mentor)
Committee memberVlatka Čubrić Čurik (predsjednik povjerenstva)
Committee memberIno Čurik (član povjerenstva)
Committee memberMaja Ferenčaković (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Agriculture
(Animal Science)
Zagreb
Defense date and country2019-09-30, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Agronomy
Abstract
Mutacije su bitne za evoluciju pa čak i one štetne. No, većinski mogu uzrokovati velike probleme i gubitke pri uzgoju životinja. Pojava besmislene mutacije na APAF1 genu dovela je do velikih novčanih gubitaka. Poznati bik, Chef, bio je idealna jedinka za stvaranje potomaka, ali je u populaciju uveo i smrtonosni gen odgovoran za oko pola milijuna spontanih pobačaja diljem svijeta. Zahvaljujući metodama sekvenciranja nove generacije pomoću kojih je pronađen uzrok nastalih gubitaka, razvijeni su dijagnostički testovi za mutaciju APAF1 koje uzgajivači mogu koristiti kako bi izbjegli parenje dva nosioca štetnih mutacija, a da pritom zadrže korisne genetske doprinose.
Abstract (english)
Mutations are essential for evolution, even the harmful ones. But mostly they can cause major problems and losses in animal breeding. The appearance of nonsense mutation on the APAF1 gene has led to large losses, population and moneywise. The famous bull, Chef, was the ideal offspring creator, but he also introduced a deadly gene responsible for about half a million spontaneous miscarriages around the world. Thanks to the new generation sequencing methods the cause of the resulting losses was found and the APAF1 mutation diagnostic tests were developed that breeders can use to avoid the mating of two carriers while retaining useful genetic contributions.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:204:220852
Study programmeTitle: Animal Genetics and Breeding
Study programme type: university
Study level: graduate
Academic / professional title: magistar/ magistra inženjer/inženjerka genetike i oplemenjivanja životinja (magistar/ magistra inženjer/inženjerka genetike i oplemenjivanja životinja)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2019-11-18 10:20:33