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undergraduate thesis
Neurobiološka podloga placebo i nocebo učinka
Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology, 2022. urn:nbn:hr:181:722501
Križanović, Kristina
Josip Juraj Strossmayer University of Osijek
Department of biology

Institutional repository: Repository of Department of biology, Josip Juraj Strossmayer University of Osijek

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Križanović, K. (2022). Neurobiološka podloga placebo i nocebo učinka (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:181:722501

Križanović, Kristina. "Neurobiološka podloga placebo i nocebo učinka." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2022. https://urn.nsk.hr/urn:nbn:hr:181:722501

Križanović, Kristina. "Neurobiološka podloga placebo i nocebo učinka." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2022. https://urn.nsk.hr/urn:nbn:hr:181:722501

Križanović, K. (2022). 'Neurobiološka podloga placebo i nocebo učinka', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:181:722501

Križanović K. Neurobiološka podloga placebo i nocebo učinka [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology; 2022 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:181:722501

K. Križanović, "Neurobiološka podloga placebo i nocebo učinka", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, Osijek, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:181:722501

Metadata
TitleNeurobiološka podloga placebo i nocebo učinka
Title (english)Neurobiological basic of placebo and nocebo effect
AuthorKristina Križanović
MentorSenka Blažetić (mentor)
Committee memberSenka Blažetić (predsjednik povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of biology
Osijek
Defense date and country2022-09-22, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Placebo i nocebo učinci oduvijek su bili predmet zanimanja mnogih znanstvenika. U početcima je placebo učinak bio okarakteriziran kao neuspjeli postupak liječenja što se u kasnijim studijama pokazalo kao netočno. Za nastanak ovih fenomena zaduženi su različiti uzročnici kao što su neurobiološka podloga, genska podloga, prethodna iskustva, očekivanja i farmakološka svojstva tvari koje se primjenjuju. Ovi uzročnici ne djeluju zasebno niti se mogu tako promatrati. Kroz mnogobrojne studije koje su ponajviše bile bazirane na istraživanju boli, dokazano je da ključne uloge u nastanku ovih učinaka imaju mnogi dijelovi mozga od kojih su najveće promjene aktivnosti zapažene u prednjem cingularnom korteksu, lateralno prefrontalnom korteksu, talamusu i insuli koji se razlikuju ovisno radili se o placebo ili nocebo učinku. Ovi učinci su uvelike zaslužni za medicinska poboljšanja liječenja jer se koriste kao neizbježni čimbenik u testiranju novih tretmana i pridonose boljem razumijevanju same bolesti koja se tretira. U novije vrijeme se raspravlja o pojavi placeba ali bez obmane ispitanika.
Abstract (english)
Placebo and nocebo effects have always been the subject of interest for many scientists. In the beginning, the placebo effect was characterized as a failed treatment process, which later studies proved to be incorrect. Various factors are responsible for the emergence of these phenomena, such as neurobiological background, genetic background, previous experiences, expectations and pharmacological properties of the substances that are used. These causative factors do not act separately, nor can they be observed as such. Through numerous studies that were mostly based on pain research, it has been proven that many parts of the brain play a key role in the emergence of these effects, of which the largest changes in activity were observed in the anterior cingulate cortex, lateral prefrontal cortex, thalamus and insula, which differ depending on what was done about the placebo or nocebo effect. These effects are largely responsible for medical improvements in treatment because they are used as an inevitable factor in testing new treatments and contribute to a better understanding of the disease being treated. Recently, the appearance of placebo has been discussed, but without deceiving the subjects.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:181:722501
Study programmeTitle: Undergraduate University Study Programme in Biology (Bachelor of Science)
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
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Created on2022-11-02 11:19:04