prikaz prve stranice dokumenta Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach
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Scientific paper - Original scientific paper
Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach
European Biophysics Journal, 28 (1999), 4; 302-311. urn:nbn:hr:193:393796
Zuvic-Butorac, Marta; Müller, Peter; Pomorski, Tomas; Libera, Jeanette; Herrmann, Andreas; Schara, Milan

Institutional repository: Repository of the University of Rijeka, Faculty of Biotechnology and Drug Development

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Zuvic Butorac, M., Müller, P., Pomorski, T., Libera, J., Herrmann, A. & Schara, M. (1999). Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach. European Biophysics Journal, 28. (4), 302-311. Retrieved from https://urn.nsk.hr/urn:nbn:hr:193:393796

Zuvic Butorac, Marta, et al. "Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach." European Biophysics Journal, vol. 28, no. 4, 1999, pp. 302-311. https://urn.nsk.hr/urn:nbn:hr:193:393796

Zuvic Butorac, Marta, Peter Müller, Tomas Pomorski, Jeanette Libera, Andreas Herrmann and Milan Schara. "Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach." European Biophysics Journal 28, no. 4 (1999): 302-311. https://urn.nsk.hr/urn:nbn:hr:193:393796

Zuvic Butorac, M., et al. (1999) 'Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach', European Biophysics Journal, 28(4), pp. 302-311. Available at: https://urn.nsk.hr/urn:nbn:hr:193:393796 (Accessed 22 November 2024)

Zuvic Butorac M, Müller P, Pomorski T, Libera J, Herrmann A, Schara M. Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach. European Biophysics Journal [Internet]. 1999 [cited 2024 November 22];28(4):302-311. Available at: https://urn.nsk.hr/urn:nbn:hr:193:393796

M. Zuvic Butorac, P. Müller, T. Pomorski, J. Libera, A. Herrmann and M. Schara, "Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach", European Biophysics Journal, vol. 28, no. 4, pp. 302-311, 1999. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:193:393796. [Accessed: 22 November 2024]

Metadata
Title (english)Lipid domains in the exoplasmic and cytoplasmic leaflet of human erythrocyte membrane; a spin label approach
AuthorMarta Zuvic-Butorac
AuthorPeter Müller
AuthorTomas Pomorski
AuthorJeanette Libera
AuthorAndreas Herrmann
AuthorMilan Schara
Author's institutionUniversity of Rijeka
(Faculty of Biotechnology and Drug Development)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Biophysics and Medical Physics
Abstract (english)
The existence of different lipid domains in the monolayers of the human erythrocyte membrane was investigated at 4 degrees C by employing spin-labelled phospholipid analogues. Spectra of analogues located exclusively either in the exoplasmic or in the cytoplasmic leaflet of erythrocyte membranes were recorded. Spectra were simulated by variation of order parameter describing the average amplitude of motion of the long molecular axis of the nitrogen 2 p pi orbital of the spin label and of the respective correlation times. For both leaflets at least three components were required to fit the experimental spectra, differing mainly in the order parameter. While the parameters of each component are not very different between both membrane halves, the relative contribution of each component to the spectrum is different between the exoplasmic and cytoplasmic leaflet. The order parameter of the most fluid component, presumably resembling the lipid bulk phase, is smaller in the cytoplasmic leaflet in comparison to the exoplasmic one. The lateral coexistence of different lipid domains in the human red blood cell membrane is concluded. The molecular nature of those domains is discussed.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleEuropean Biophysics Journal
Numberingvol. 28, no. 4, pp. 302-311
p-ISSN0175-7571
e-ISSN1432-1017
URN:NBNurn:nbn:hr:193:393796
Publication1999
Document URLhttps://www.ncbi.nlm.nih.gov/pubmed/10394622
Type of resourceText
Access conditionsClosed access
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Created on2018-09-30 18:46:02