Macroeconomic changes are very rarely studied as a source of business opportunities for new entrepreneurial ventures. Macroeconomic changes are happening fast and their consequences have a lasting effect on national and world economies. They are most often analyzed when it comes to global crises, and their impact on business, government assistance programs to vulnerable businesses, and the damage they cause at the level of national economies. In the first part of this final paper, the business environment is defined, as well as the basic segments of the business environment that represent one of the key factors for a quality perception of the business opportunity. The paper will explain that not every idea is also a business opportunity and that business opportunities are not always recognized in a simple way. In this paper, we will talk about how recognizing business opportunities is a challenge for every entrepreneur, and especially for those who use different methods and techniques that help him identify different business opportunities. The aim of this final paper is to describe the environment in which business entities operate on the market of the Republic of Croatia (RH), and the impact of the most important macroeconomic changes on the business environment of the Croatian market in the last ten years. Using Green's business opportunity model (2015), the paper will show how macroeconomic changes are changing the business environment and creating new business opportunities. Special emphasis in this paper will be placed on the crisis that all world economies are going through, the so-called corona crisis, and the sources of business opportunities that are currently emerging in the market.