The topic of this paper refers to the role and influence of the Zagorje Development Agency one entrepreneurship in the Krapina-Zagorje County. The purpose of the paper is to provide insight into the significance and role of the Zagorje Development Agency on the development of entrepreneurial activities in the Krapina-Zagorje County. In order to achieve the above-mentioned goal, methods for analysing the economic trends in the Krapina-Zagorje County were used. An empirical analysis was performed to investigate the competitiveness in the field of entrepreneurship, whereas the position of the economy of the Krapina-Zagorje County within Croatia was established based on the results of a comparative analysis. The strategic analysis showed the advantages of the Krapina-Zagorje County and its potential for creating future entrepreneurial activities. These section of the paper that refers to the significance and purpose of the Zagorje Development Agency describes its activities by areas, the significance of the same as well as the operating methods used to achieve positive results. The mentioned section serves as an introduction to the main purpose and goals of this paper as well as the results achieved, and conclusions made. Furthermore, the main part of the paper includes examples from and analyses of the general condition of the economy of the Krapina-Zagorje County, the level of entrepreneurship development, and the position of the economy of the Krapina-Zagorje County within Croatia. It also gives an explanation and over view of the models of cooperating with entrepreneurs ensuring success in the market. Finally, the paper emphasizes the competitiveness and market position of entrepreneurs as one of the important facts in the development of small and medium-sized enterprises. Entrepreneurship development is not simple, as we are speaking of a very dynamic economic category that quickly reflects on all market changes.