Hospitalizations of children can represent significant stress and shock with intense feelings of sadness, fear, but also anger due to separation from family and everyday environment. Depending on the age, children react differently to staying in the hospital and to the new situation in general related to their health condition. Some children may experience hospitalization as punishment and develop a sense of guilt by thinking that they have contributed to it through their behavior and actions. Because of all of all the above, many preventive measures and adjustments are needed in the pediatric departments in order for the child to have a better and more comfortable stay in the hospital, as much as possible given the diagnosis and condition. Chronic kidney disease is a term that refers to the gradual and irreversible loss of kidney function. The incidence of progressive kidney disease in people under the age of 18 is estimated to be 6 to 8 children / 1,000,000 population per year. The most common causes of progressive renal failure in the pediatric population are congenital anomalies of the kidneys and urinary system, cystic kidney disease and glomerular disease. Due to the severity of the clinical picture, these children are subjected to frequent hospitalizations due to various complications, examinations and procedures, but also dialysis when there is an advanced stage of kidney disease and transplantation. Therefore, the thesis presents a qualitative study aimed at gaining insight into the experiences of mothers of children with chronic kidney disease on the significance of frequent hospitalizations for their children's development, adapting the hospital environment to individual needs and difficulties of children, communication with medical staff and experiences related to the separation of mother and child during hospitalizations as well as their reflections on the necessary changes in the health care system in pediatric wards. The research was conducted through a semi-structured interview with six mothers from the Republic of Croatia. Significant answers related to the described problems have emerged, which can contribute to better quality systematic care for children, but also for mothers and, ultimately, for the whole family