Children with disabilities have different physical, mental, and social characteristics that make it difficult for them to effectively and frequently practice dental care. In this group of children, the underlying disease is the primary focus, while the condition in the oral cavity is usually paid attention to only when problems start. Prevention of the disease is extremely important here, as it is difficult to carry out any interventions in this population. Proper and regular oral hygiene is facilitated by the existence of certain modifications to the toothbrush. In addition to the toothbrush, it is advisable to use fluoride, which helps strengthen the enamel. In addition, it is important to conduct regular check-ups and prophylactic procedures in the office and to advise parents/guardians on nutrition. For the doctor to make the examination and the necessary procedures, it is important to establish a relationship of trust between the child and the parents/guardians. Each DSPP is unique, and the Doctor of Dental Medicine should treat everyone as such with a maximally individualized approach in the office and an individualized plan of preventive procedures, and if necessary, invasive procedures.