prikaz prve stranice dokumenta Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial
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Scientific paper - Original scientific paper
Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial
Antibiotics, 10 (2021), 8; 924. https://doi.org/10.3390/antibiotics10080924
Pilloni, Andrea; Zeza, Blerina; Kuiš, Davor; Vražić, Domagoj; Domić, Tomislav; Olszewska- Czyz, Iwona; Popova, Christina; Kotsilkov, Kamen; Firkova, Elena; Dermendzieva, Yana; Tasheva, Angelina; Orrù, Germano; Sculean, Anton; Prpić, Jelena

Institutional repository: Repository of the University of Rijeka, Faculty of Dental Medicine

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Pilloni, A., Zeza, B., Kuiš, D., Vražić, D., Domić, T., Olszewska Czyz, I. ... Prpić, J. (2021). Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial. Antibiotics, 10. (8). doi: 10.3390/antibiotics10080924

Pilloni, Andrea, et al. "Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial." Antibiotics, vol. 10, no. 8, 2021. https://doi.org/10.3390/antibiotics10080924

Pilloni, Andrea, Blerina Zeza, Davor Kuiš, Domagoj Vražić, Tomislav Domić, Iwona Olszewska Czyz, Christina Popova, et al. "Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial." Antibiotics 10, no. 8 (2021). https://doi.org/10.3390/antibiotics10080924

Pilloni, A., et al. (2021) 'Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial', Antibiotics, 10(8). doi: 10.3390/antibiotics10080924

Pilloni A, Zeza B, Kuiš D, Vražić D, Domić T, Olszewska Czyz I, and sur.. Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial. Antibiotics [Internet]. 2021 [cited 2024 November 07];10(8). doi: 10.3390/antibiotics10080924

A. Pilloni, et al., "Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial", Antibiotics, vol. 10, no. 8, 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:271:325831. [Accessed: 07 November 2024]

Metadata
Title (english)Treatment of Residual Periodontal Pockets Using a Hyaluronic Acid-Based Gel: A 12 Month Multicenter Randomized Triple-Blinded Clinical Trial
AuthorAndrea Pilloni
AuthorBlerina Zeza
AuthorDavor Kuiš
AuthorDomagoj Vražić
MBZ: 317142
AuthorTomislav Domić
AuthorIwona Olszewska- Czyz
AuthorChristina Popova
AuthorKamen Kotsilkov
AuthorElena Firkova
AuthorYana Dermendzieva
AuthorAngelina Tasheva
AuthorGermano Orrù
AuthorAnton Sculean
AuthorJelena Prpić
Author's institutionUniversity of Rijeka
(Faculty of Dental Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Periodontology
Abstract (english)
The aim of the present study was to evaluate the adjunctive effect of hyaluronic acid (HA) gel in the treatment of residual periodontal pockets over a 12-month period. Periodontal patients presenting at least one residual periodontal pocket 5-9 mm of depth in the anterior area were recruited from six university-based centers. Each patient was randomly assigned to subgingival instrumentation (SI) with the local adjunctive use of HA for test treatment or adjunctive use of local placebo for control treatment at baseline and after 3 months. Clinical parameters ( )probing depth (PD), bleeding on probing (BoP), plaque index (PI), recession (REC), clinical attachment level (CAL)) and microbiological samples for the investigation of the total bacterial count (TBC) and presence of specific bacterial species (Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Fusobacterium nucleatum) were taken at baseline and every 3 months, until study termination. PD was determined as the primary outcome variable. From a total of 144 enrolled, 126 participants (53 males, 73 females) completed the entire protocol. Both treatments resulted in statistically significant clinical and microbiological improvements compared to baseline. Although the local application of HA showed a tendency for better results, there was a lack of statistically significant differences between the groups.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAntibiotics
Numberingvol. 10, no. 8, 924
e-ISSN2079-6382
DOIhttps://doi.org/10.3390/antibiotics10080924
URN:NBNurn:nbn:hr:271:325831
Publication2021
Document URLhttp://bib.irb.hr/1161102
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2023-01-23 07:34:00