Aim: Examine the emotional functioning and self-perception of women with breast cancer in relation to age, education, place of residence and method of treatment. Study design: Cross-sectional research. Patients and methods: 81 respondents participated in the research. It was conducted at the Department of Oncology of the Osijek Clinical Hospital Center during April 2022 using the adapted Croatian version of the anonymous questionnaire The Functional Assessment of Cancer Therapy - Breast (FACT-B). The emotional functioning and additional concerns scales were used. A higher number of points on the particles indicates better functioning, apropos a higher number of symptoms. The survey is scored on a Likert scale. The SPSS statistical program is used for statistical analysis. Results: The median age of the subjects was 58 years, and the most common method of treatment was cytostatic in 72 of the subjects (89 %). More than half of the respondents believe that hair loss is a visible reminder that they suffer from breast cancer and they are insecure about the way they dress and do not feel sexually attractive. Respondents in the age group of 70 and older significantly agree with the statement that they are satisfied with how they cope with their illness, in contrast to respondents in younger age groups. Respondents aged 30 - 39 and 40 - 49 are more bothered by changes in body weight, unlike respondents aged 70 and over. Conclusion: Patients of the younger age group have a worse self-perception and are more bothered by changes in body weight. Respondents in the age group of 70 and over are more satisfied with how they cope with the disease than patients in younger age groups. Subjects who are undergoing hormone therapy and immunotherapy feel more sexual. There is no significant difference in the emotional functioning and self-perception of the respondents with regard to the level of education and place of residence.