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undergraduate thesis
Hibridni pristup kod sastavljanja genoma de novo
Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing, 2016. urn:nbn:hr:168:893975
Franjić, Marko
University of Zagreb
Faculty of Electrical Engineering and Computing

Institutional repository: FER Repository

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Franjić, M. (2016). Hibridni pristup kod sastavljanja genoma de novo (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing. Retrieved from https://urn.nsk.hr/urn:nbn:hr:168:893975

Franjić, Marko. "Hibridni pristup kod sastavljanja genoma de novo." Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2016. https://urn.nsk.hr/urn:nbn:hr:168:893975

Franjić, Marko. "Hibridni pristup kod sastavljanja genoma de novo." Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, 2016. https://urn.nsk.hr/urn:nbn:hr:168:893975

Franjić, M. (2016). 'Hibridni pristup kod sastavljanja genoma de novo', Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, accessed 28 December 2024, https://urn.nsk.hr/urn:nbn:hr:168:893975

Franjić M. Hibridni pristup kod sastavljanja genoma de novo [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Electrical Engineering and Computing; 2016 [cited 2024 December 28] Available at: https://urn.nsk.hr/urn:nbn:hr:168:893975

M. Franjić, "Hibridni pristup kod sastavljanja genoma de novo", Undergraduate thesis, University of Zagreb, Faculty of Electrical Engineering and Computing, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:168:893975

Metadata
TitleHibridni pristup kod sastavljanja genoma de novo
Title (english)Hybrid de novo genome assembly
AuthorMarko Franjić
MentorMirjana Domazet-Lošo (mentor)
Committee memberMirjana Domazet-Lošo (predsjednik povjerenstva)
Committee memberMario Brčić (član povjerenstva)
Committee memberMarina Ptiček (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Electrical Engineering and Computing
Zagreb
Defense date and country2016-07-11, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Computing
Abstract
Slaganje genoma postupak je kojim se bavi interdisciplinarna disciplina bioinformatika. Glavni koraci su sekvenciranje genoma u očitanja, algoritamska razrada problema, asembliranje te obrada dobivenih podataka. U radu se izrađuje programsko rješenje koje nastoji prikazati postupak hibridnog sastavljanja genoma od samih generiranja očitanja, preko njihove algoritamske obrade, pa sve do asembliranja u jedan niz. Početna se očitanja virtualno generiraju po uzoru na dvije suvremene tehnologije, Oxford Nanopore MinION te Illumina. Dodatno, u drugom djelu rada provodi se statistička analiza koja rezultira optimalnim parametrima korištenja programa. Na kraju su objašnjene sličnosti i razlike između ovog programskog rješenja i programa NaS koji se temelji na istom hibridnom de novo principu sastavljanja genoma.
Abstract (english)
Genome assembly is a procedure that is being developed and researched by an interdisciplinary field called bioinformatics. Main parts of the assembly are genome sequencing, using the reconstruction algorithms, reconstruction to a goal sequence and the analysis of the results. As a part of the thesis, the software solution attempts to demonstrate a procedure of hybrid reconstruction of genome from the very first generated genome reads to a complete assembly of a goal string. Original genome reads which are used in the process of assembly are being virtually generated to represent the reads one would acquire while using two different modern sequencing technologies, Oxford Nanopore MinION and Illumina. Furthermore, the result analysis is being covered in the second part of the thesis which gives optimal parameters that are being used in the software solution. At the end, the crucial similarities and differences are being explained between this solution and program called NaS which is based on the same hybrid de novo genome assembly principle.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:168:893975
Study programmeTitle: Computing
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka računarstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka računarstva)
Type of resourceText
File originBorn digital
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Created on2018-02-06 08:46:22