The aim of this study was to examine the role of the behavioral immune system in the perception of the characteristics of male faces. The relationship between the current health status of male faces, the phase of the menstrual cycle in which these faces were evaluated and the assessment of the attractiveness, pleasantness, threat and repulsion of the presented faces was examined. Adult women with regular menstrual cycles who do not use contraceptive pills participated in the online experiment. The same participants (N = 41) in the early follicular, late follicular and mid-luteal phase of the menstrual cycle provided ratings for healthy and sick versions of male faces shown in photographs. The sick versions of the face were obtained by manipulating the healthy versions of the face whereby the manipulated features were the color of the skin, under-eye circles and the position of the corners of the lips. The results showed that the sick versions of the face were evaluated as less attractive and less pleasant and more threatening and repulsive than the healthy versions. This is consistent with the assumption of activation of the behavioral immune system in response to the perception of cues of possible infection. But, contrary to expectations, the evaluations of the healthy and sick versions of the face were similar in all three phases of the cycle, i.e., there was no increase in sensitivity to disease cues in phases with elevated levels of sex hormones. Hereby the hypothesis of greater sensitivity to disease cues during the luteal phase of the cycle, when immunosuppression occurs under the influence of progesterone, has not been confirmed.