Amongst psychological disorders, anxiety and depressive disorders are the most frequently mentioned today. Many factors such as high anxiety sensitivity, high environmental sensitivity and using maladaptive emotional regulation techniques cause and influence the development of these disorders. This research analyses the relationships between these factors, including the moderating role that maladaptive and adaptive emotional regulation techniques could play in the background on the relationship between the two types of sensitivity. It also examines the mediating role that maladaptive emotional regulation techniques have in relation to two types of sensitivity and life satisfaction. 367 people (77.1% women) participated in the research. The Anxiety Sensitivity Index and the abbreviated version of the Environmental Sensitivity Scale for Adults were used to measure two types of sensitivity. Emotional regulation was measured by the Cognitive Emotional Regulation Questionnaire. The results showed a strong positive association between anxiety sensitivity, environmental sensitivity and maladaptive emotional regulation techniques, and they were negatively related to life satisfaction. Also the findings show that maladaptive emotional regulation techniques contribute to the strenght of the association between anxiety sensitivity and environmental sensitivity. It was also shown that the relationship between the two types of sensitivity and life satisfaction can be explained by the use of maladaptive emotional regulation techniques. These results have implications in the fields of clinical psychology and counseling.