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undergraduate thesis
Sorpcija trimetoprima na prirodne uzorke tla i sedimente
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. urn:nbn:hr:149:515536
Barbir, Vendi
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Barbir, V. (2019). Sorpcija trimetoprima na prirodne uzorke tla i sedimente (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:515536

Barbir, Vendi. "Sorpcija trimetoprima na prirodne uzorke tla i sedimente." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. https://urn.nsk.hr/urn:nbn:hr:149:515536

Barbir, Vendi. "Sorpcija trimetoprima na prirodne uzorke tla i sedimente." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. https://urn.nsk.hr/urn:nbn:hr:149:515536

Barbir, V. (2019). 'Sorpcija trimetoprima na prirodne uzorke tla i sedimente', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:515536

Barbir V. Sorpcija trimetoprima na prirodne uzorke tla i sedimente [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2019 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:515536

V. Barbir, "Sorpcija trimetoprima na prirodne uzorke tla i sedimente", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:149:515536

Metadata
TitleSorpcija trimetoprima na prirodne uzorke tla i sedimente
Title (english)Sorption of trimethoprim on natural soil and sediment samples
AuthorVendi Barbir
MentorDragana Mutavdžić Pavlović (mentor)
Committee memberDragana Mutavdžić Pavlović (predsjednik povjerenstva)
Committee memberŠime Ukić (član povjerenstva)
Committee memberTatjana Gazivoda Kraljević (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2019-09-17, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Trimetoprim je farmaceutski aktivna tvar koja se najčešće koristi za liječenje infekcija mokraćnog sustava, upala srednjega uha i dijareje. On je bakteriostatik koji se veže na bakterijski enzim te inhibira metabolizam folne kiseline. Raspoloživ je kao samostalan lijek ili u kombinacijama s drugim tvarima, a kombinacija trimetoprim-sulfametoksazol je oblik koji se najčešće koristi. Iako je jedan od najčešće korištenih antibiotika njegov utjecaj na okoliš nije dobro istražen, stoga se u ovom radu ispitivala sorpcija trimetoprima na 5 realnih uzoraka tla i 5 realnih uzoraka sedimenata s područja Republike Hrvatske. Dobiveni rezultati prikazani su linearnom, Freundlichovom i Dubinin-Radushkevichevom sorpcijskom izotermom. Vrijednosti koeficijenta sorpcije, Kd za uzorke tla su od 18,10 mLg^-1 do 153,08 mLg^-1, a za uzorke sedimenata od 35,19 mLg^-1 do 93,20 mLg^-1. U radu je ispitana i prikazana kinetika, ionska jakost te utjecaj vrijednosti pH na sorpciju otopine trimetoprima. Rezultati pokazuju da porastom ionske jakosti koeficijent sorpcije trimetoprima se smanjuje, a raste s porastom pH-vrijednosti.
Abstract (english)
Trimethoprim is a pharmaceutical active substance commonly used to treat urinary tract infections, middle ear inflammation, and diarrhea. It is bacteriostatic that binds to a bacterial enzyme and inhibits folic acid metabolism. It is available as a stand-alone drug or in combination with other substances, and the trimethoprim-sulfamethoxazole combination is the most commonly used form. Although one of the most commonly used antibiotics, its environmental impact has not been well investigated. In order to find out its effect on the environment, we have examined its sorption on 5 real soil samples and 5 real sediment samples from the territory of the Republic of Croatia. The obtained results are presented by linear, Freundlich and Dubinin-Radushkevich sorption isotherms. The values of sorption coefficient, Kd for soil samples are from 18.10 mLg^-1 to 153.08 mLg^-1, and for sediment samples from 35.19 mLg^-1 to 93.20 mLg^-1. The kinetics, the influence of ionic strength and the influence of pH value on sorption of trimethoprim were also examined and presented in the paper. The results show that with increasing ionic strength, the sorption coefficient of trimethoprim decreases and increases with increasing of pH value.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:515536
ProjectNumber: IP-2014-09-2353
Title: Sudbina farmaceutika u okolišu i tijekom naprednih postupaka obrade voda
Title: Fate of pharmaceuticals in the environment and during advanced wastewater treatment
Acronym: PharmaFate
Leader: Sandra Babić
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Chemical Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2023-02-13 12:20:26