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undergraduate thesis
Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2022. urn:nbn:hr:149:128987
Borić, Ingo
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Borić, I. (2022). Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:128987

Borić, Ingo. "Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2022. https://urn.nsk.hr/urn:nbn:hr:149:128987

Borić, Ingo. "Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2022. https://urn.nsk.hr/urn:nbn:hr:149:128987

Borić, I. (2022). 'Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:128987

Borić I. Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2022 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:149:128987

I. Borić, "Sinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:149:128987

Metadata
TitleSinteza i spektroskopska karakterizacija novih heterostilbenskih derivata 4-pirona i njihovo kompleksiranje s biometalima
Title (english)Synthesis and spectroscopic characterization of new heterostilbene derivatives of 4-pyrone and their complexation with biometals
AuthorIngo Borić
MentorIrena Škorić (mentor)
Committee memberIrena Škorić (predsjednik povjerenstva)
Committee memberDragana Vuk (član povjerenstva)
Committee memberLidija Furač (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2022-07-07, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
S ciljem pronalaska novih potencijalnih inhibitora kolinesteraza sintetizirani su novi heterostilbenski derivati 4-pirona. Wittigovom reakcijom sintetizirane su cis- i trans- heterostilbenske strukture iz određenih aldehida i fosfonijevih soli 4-pirona. Ukupno je dobiveno i izolirano deset heterostilbenskih 4-pironskih derivata. Svi produkti pročišćeni su kolonskom kromatografijom, a strukture su im okarakterizirane i potvrđene 1H, 13C i 2D NMR spektrima te UV i IR spektrima. Kristalne strukture dva pironska heterostilbena dodatno potvrđuju strukturu i pakiranje dobivenih spojeva, a ispitano je i njihovo kompleksiranje s biometalima kao i utjecaj temperature na kemijske pomake u NMR spektrima.
Abstract (english)
In order to find new potential cholinesterase inhibitors, new heterostilbene derivatives of 4-pyrone were synthesized. The Wittig reaction yielded cis- and trans-heterostilbene structures from certain aldehydes and phosphonium salts of 4-pyrone. A total of ten 4-pyrone heterostilbene derivatives were obtained and isolated. All products were purified by column chromatography, and their structures were characterized and confirmed by 1H, 13C and 2D NMR spectra and UV and IR spectra. The crystal structures of two of them further confirm the structure and the packing of the obtained compounds. Additionally their complexation with biometals has been investigated as well as the influence of the temperature on the chemical shifts in the NMR spectra.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:128987
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2023-02-21 07:31:02