prikaz prve stranice dokumenta Modeliranje topljivosti rivaroksabana u organskim otapalima
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undergraduate thesis
Modeliranje topljivosti rivaroksabana u organskim otapalima
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. urn:nbn:hr:149:467038
Antolković, Ana
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Antolković, A. (2021). Modeliranje topljivosti rivaroksabana u organskim otapalima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:467038

Antolković, Ana. "Modeliranje topljivosti rivaroksabana u organskim otapalima." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:467038

Antolković, Ana. "Modeliranje topljivosti rivaroksabana u organskim otapalima." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:467038

Antolković, A. (2021). 'Modeliranje topljivosti rivaroksabana u organskim otapalima', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:467038

Antolković A. Modeliranje topljivosti rivaroksabana u organskim otapalima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2021 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:149:467038

A. Antolković, "Modeliranje topljivosti rivaroksabana u organskim otapalima", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:149:467038

Metadata
TitleModeliranje topljivosti rivaroksabana u organskim otapalima
Title (english)Modeling of the solubility of rivaroxabane in organic solvents
AuthorAna Antolković
MentorMarko Rogošić (mentor)
Committee memberMarko Rogošić (predsjednik povjerenstva)
Committee memberAleksandra Sander (član povjerenstva)
Committee memberKristina Zagajski Kučan (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2021-09-21, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Chemical Engineering
Abstract
U ovom radu opisani su načini modeliranja fazne ravnoteže kapljevina-krutina za antikoagulantni lijek rivaroksaban oblika I i II u sljedećim otapalima: acetonitril, metil-acetat, 1,4-dioksan, aceton, 2-butanon, 3-pentanon i 2-heksanon. Izračunati su interakcijski parametri četiriju modela koeficijenta aktivnosti: Wilson, NRTL, UNIQUAC i COSMO-RS koristeći eksperimentalne podatke o topljivosti rivaroksabana. Kao rezultat dobiveni su fazni dijagrami topljivosti za sva četiri modela te grafički prikaz krivulje taljenja određene prema modelima. Raspravljena je mogućnost primjene pojedinih modela za ispitivane sustave.
Abstract (english)
This paper describes methods for modeling the liquid-solid phase equilibria for the anticoagulant drug rivaroxaban forms I and II in the following solvents: acetonitrile, methyl acetate, 1,4-dioxane, acetone, 2-butanone, 3-pentanone and 2-hexanone. Interaction parameters of four activity coefficient models: Wilson, NRTL, UNIQUAC and COSMO-RS were calculated from experimental solubility data of rivaroxaban. As a result, solubility phase diagrams were obtained for all four models and a graphical representation of the liquidus curve determined by the models. The possibility of applying particular models for examined systems is discussed.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:467038
Study programmeTitle: Chemical Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsClosed access
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Created on2023-03-23 08:54:02