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undergraduate thesis
Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. urn:nbn:hr:149:464341
Petrin, Damjan
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Petrin, D. (2021). Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:464341

Petrin, Damjan. "Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:464341

Petrin, Damjan. "Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:464341

Petrin, D. (2021). 'Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:464341

Petrin D. Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2021 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:149:464341

D. Petrin, "Razvoj i validacija kromatografske metode za određivanje venlafaksina u vodi", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:149:464341

Metadata
TitleRazvoj i validacija kromatografske metode za određivanje venlafaksina u vodi
Title (english)Development and validation of a chromatographic method for the determination of venlafaxine in water
AuthorDamjan Petrin
MentorSandra Babić (mentor)
Committee memberSandra Babić (predsjednik povjerenstva)
Committee memberDragana Mutavdžić Pavlović (član povjerenstva)
Committee memberIrena Škorić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2021-09-03, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Analitička kemija od velikog je značaja za industrijski i znanstveni svijet. Konstantno provođenje analiza važno je za razvoj i kontrolu kvalitete proizvoda, a time i za kvalitetu ljudskog života. Nakon razvijanja neke analitičke metode, prvi nužan korak jest njena validacija. Validacija je postupak kojim se utvrđuje prikladnost metode za neku zamišljenu svrhu, a provodi se ispitivanjem niza karakteristika koje se zatim uspoređuju s propisanim zahtjevima (kriterijima). Karakteristike koje se ispituju pri validaciji su linearnost, osjetljivost, preciznost, selektivnost, granica detekcije, granica kvantifikacije, radno područje, istinitost i robustnost. Cilj ovog rada bio je razviti i validirati kromatografsku HPLC-PDA metodu za određivanje venlafaksina u riječnim vodama. Izvedbene karakteristike metode ispitane su u dvije različite matrice, u deioniziranoj i u riječnoj vodi. Sve izvedbene karakteristike zadovoljile su postavljene kriterije pa je ova metoda okarakterizirana kao ispravna za određivanje venlafaksina u riječnoj vodi. Također su opisani i instrumenti koji su korišteni u izvedbi eksperimentalnog dijela te njihov način rada, a detaljnije je opisan proces kromatografije i postupak rada na kromatografskom uređaju.
Abstract (english)
Analytical chemistry is important both in scientific research and in industrial applications. Regular or continuous analyses are essential for the development and quality control of products and hence for the quality of life. After the development of an analytical method, the first necessary step is its validation. It is the process by which the applicability for a definite purpose is critically and carefully quantitatively examined with respect to a list of required characteristic criteria. The properties examined in the validation are linearity, sensitivity, precision, selectivity, limit of detection, limit of quantification, working range, trueness and robustness. The aim of the present study is to develop and validate a chromatographic HPLC-PDA method for the quantitative determination of venlafaxine in river waters. The validation criteria have been determined in two matrices: deionized water and river water. All the given criteria have been met so that the present method could be declared as valid for the determination of venlafaxine in river waters. In addition, the instruments used in the experimental procedure and the principles of their operation are described. The process of chromatography and work with chromatographic equipment are given in greater detail.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:464341
Study programmeTitle: Materials Science and Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2022-09-01
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Created on2023-04-13 11:00:37