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undergraduate thesis
HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. urn:nbn:hr:149:273120
Priselec, Paula
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Priselec, P. (2021). HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:273120

Priselec, Paula. "HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:273120

Priselec, Paula. "HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:273120

Priselec, P. (2021). 'HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:273120

Priselec P. HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2021 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:273120

P. Priselec, "HPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:149:273120

Metadata
TitleHPLC metoda za ispitivanje sadržaja lurasidon-hidroklorida u minitabletama
Title (english)HPLC method for the study of lurasidone hydrochloride content in mini-tablets
AuthorPaula Priselec
MentorKrunoslav Žižek (mentor)
Committee memberKrunoslav Žižek (predsjednik povjerenstva)
Committee memberMarin Kovačić (član povjerenstva)
Committee memberDanijela Ašperger (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2021-09-10, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Chemical Engineering
Abstract
Istraživanje se provodi na raspadljivim minitabletama lurasidon-hidroklorida dobivenim različitim postupcima priprave u prethodnom istraživanju. U pripravi minitableta promjera 3 mm korišteni su liofilizati i granulirane mješavine s ugrađenom djelatnom tvari. Korišteni su manitol, natrijeva kroskarmeloza te mikrokristalna celuloza kao pomoćne tvari. U određivanju sadržaja djelatne tvari u minitabletama korištene su usporedno dvije metode, kapljevinska kromatografija visoke djelotvornosti i UV/Vis-spektrofotometrija. Istraživanje podrazumijeva pronalaženje pogodnih uvjeta provedbe procesa kromatografije koji će rezultirati uspješnom kvantitativnom analizom lurasidon-hidroklorida u ovom novom ponešto drugačijem dozirnom obliku. Uspoređuju se rezultati sadržaja djelatne tvari dobiveni različitim metodama.
Abstract (english)
Study is carried on disintegrating mini-tablets of lurasidone hydrochloride obtained by different preparation procedures in previous research. Lyophilisates and granulated mixtures with incoporated drug were used in the preparation of mini-tablets with 3 mm in diameter. Mannitol, sodium croscarmellose and microcrystalline cellulose were used as excipients. Two methods, high perfomance liquid chromatography and UV/Vis-spectrophotometry, were used at the same time to detect the drug content in mini-tablets. Research connotes finding the proper conditions for running chromatography process that will result in successfull quantitative analysis of lurasidone hydrochloride in this new somewhat different dosage form. Results of drug content are compared for different methods used.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:273120
Study programmeTitle: Materials Science and Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2021-09-10
Terms of useLicence In copyright icon
Created on2023-04-14 08:06:14