prikaz prve stranice dokumenta Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije
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master's thesis
Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. urn:nbn:hr:149:433596
Penava, Ana
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Penava, A. (2021). Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije (Master's thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:433596

Penava, Ana. "Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije." Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:433596

Penava, Ana. "Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije." Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:149:433596

Penava, A. (2021). 'Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije', Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 29 March 2025, https://urn.nsk.hr/urn:nbn:hr:149:433596

Penava A. Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije [Master's thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2021 [cited 2025 March 29] Available at: https://urn.nsk.hr/urn:nbn:hr:149:433596

A. Penava, "Sinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije", Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:149:433596

Metadata
TitleSinteza novih derivata Schiffovih baza purinskih bioizostera metodama zelene kemije
Title (english)Synthesis of novel Schiff base derivatives of purine bioisosteres using green chemistry
AuthorAna Penava
MentorSilvana Raić-Malić (mentor)
Committee memberSilvana Raić-Malić (predsjednik povjerenstva)
Committee memberAndrijana Meščić Macan (član povjerenstva)
Committee memberLidija Furač (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2021-09-27, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
U okviru ovog rada provedena je sinteza i spektroskopska karakterizacija novih derivata Schiffovih baza purinskih bioizostera: benzotiazola (13a–13d, 18a–18d), benzoksazola (14a–14d, 19a–19d )i imidazo[1,2-a]piridina (15a–15d). Za pripravu ciljnih spojeva upotrijebljene su klasične metode organske sinteze i sinteza potpomognuta ultrazvučnim zračenjem. Dvostupnjevitom linearnom sintezom priređeni su amino-supstituirani prekursori benzotiazola 6, benzoksazola 7 i imidazo[1,2-a]piridin 11 iz... More odgovarajućih nitro derivata 4, 5 i 10. Ciljani hibridi Schiffovih baza benzotiazola, benzoksazola i imidazo[1,2-a]piridina pripravljeni su iz prethodno priređenih heterocikličkih primarnih amina i različito supstituiranih 2-hidroksibenzaldehida metodama klasične organske sinteze i motodama zelene kemije primjenom ultrazvučnog zračenja u etanolu i glicerolu. Strukture svih priređenih spojeva potvrđene su 1H i 13C NMR spektroskopijom. Less
Abstract (english)
This paper describes synthesis and spectroscopic characterization of novel Schiff base derivatives of purine bioisosteres: benzothiazoles 13a–13d, 18a–18d, benzoxazoles 14a–14d, 19b–19c and imidazo[1,2-a]pyridines 15a–15d prepared by conventional synthetic methods and by using ultrasonic irradiation. The main amino-substituted precursors of benzothiazole 6, benzoxazole 7 and imidazo [1,2-a]pyridine 11 were prepared by two-step linear synthesis from corresponding nitro derivateves 4, 5... More andi 10. Target hybrids of Schiff bases of benzothiazole, benzoxazole and imidazo[1,2-a]pyridine were synthesized from prepared heterocycle primary amines and variously substituted 2-hydroxybenzaldehydes by conventional synthetic methods and by green synthesis using ultrasonic irradiation with ethanol and glycerol as solvents. Structures of all synthesized compounds were confirmed by 1H and 13C NMR spectroscopy. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:433596
ProjectNumber: IP-2018-01-4682
Title: Novi spojevi temeljeni na bioizosterima purina za ispitivanje njihovih antitumorskih i antipatogenih djelovanja
Acronym: PurBioCaPa
Leader: Silvana Raić-Malić
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Applied Chemistry - Graduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra primijenjene kemije (magistar/magistra primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2023-04-19 14:12:51
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