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undergraduate thesis
Matematički model biotransformacije akrilne kiseline
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2020. urn:nbn:hr:149:912356
Bičanić, Stjepan
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Bičanić, S. (2020). Matematički model biotransformacije akrilne kiseline (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:912356

Bičanić, Stjepan. "Matematički model biotransformacije akrilne kiseline." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2020. https://urn.nsk.hr/urn:nbn:hr:149:912356

Bičanić, Stjepan. "Matematički model biotransformacije akrilne kiseline." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2020. https://urn.nsk.hr/urn:nbn:hr:149:912356

Bičanić, S. (2020). 'Matematički model biotransformacije akrilne kiseline', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 03 June 2024, https://urn.nsk.hr/urn:nbn:hr:149:912356

Bičanić S. Matematički model biotransformacije akrilne kiseline [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2020 [cited 2024 June 03] Available at: https://urn.nsk.hr/urn:nbn:hr:149:912356

S. Bičanić, "Matematički model biotransformacije akrilne kiseline", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:149:912356

Metadata
TitleMatematički model biotransformacije akrilne kiseline
Title (english)Mathematical model of acrylic acid biotransformation
AuthorStjepan Bičanić
MentorMartina Sudar (mentor)
Committee memberMartina Sudar (predsjednik povjerenstva)
Committee memberZvjezdana Findrik Blažević (član povjerenstva)
Committee memberMarija Vuković Domanovac (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2020-07-10, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Chemical Engineering
Abstract
U ovom radu ispitan je utjecaj osjetljivosti kinetičkih parametara u enzimskoj reakciji između α-ketoglutarne i akrilne kiseline kataliziranoj enzimom 2-sukcinil-5-enolpiruvil-6-hidroksi-3-cikloheksen-1-karboksilne kiseline (MenD) uz tiamin difosfat kao koenzim i magnezijev ion kao kofaktor. Osim produkta, u ovoj reakciji nastaje i nepoznati nusprodukt. Kemijski identitet nusprodukta nije poznat, ali njegovo nastajanje je potrebno uzeti u obzir prilikom razvoja matematičkog modela. Kinetička jednadžba koja opisuje nastanak nusprodukta jednaka je jednadžbi za nastanak produkta. Simulacije napravljene u ovom radu su provedene u Microsoft Excelu korištenjem Eulerove numeričke metode. Dobiveni rezultati simulacija su pokazali da su kinetički parametri koji utječu najviše na konačnu koncentraciju produkta i nusprodukta 𝑉𝑚 i 𝑉𝑚1.
Abstract (english)
In this work, the influence of kinetic parameter sensitivity in the enzymatic reaction between α-ketoglutaric and acrylic acid catalyzed by the enzyme 2-succinyl-5-enolpyruvil-6-hydroxy-3-cyclohexene-1-carboxylic acid (MenD) in the presence of thiamine diphosphate as a coenzyme and magnesium ion as a cofactor was investigated. In this reaction, in addition to the product, an unknown by-product is formed. The chemical identity of the by-product is not known, but its formation had to be taken into account when developing the mathematical model. The kinetic equation describing the formation of the by-product is equal to the equation for the formation of the product. Simulations presented in this work were carried out in Microsoft Excel using Euler’s numerical method. The obtained simulation results showed that the kinetic parameters with the highest effect on the final concentration of product and by-product are 𝑉𝑚 and 𝑉𝑚1.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:912356
Study programmeTitle: Environmental Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka ekoinženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka ekoinženjerstva)
Type of resourceText
File originBorn digital
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Created on2023-05-02 12:03:16