prikaz prve stranice dokumenta Sinteza i strukturna karakterizacija novih derivata benztiazola
Embargo period 2025-10-01
undergraduate thesis
Sinteza i strukturna karakterizacija novih derivata benztiazola
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2020. urn:nbn:hr:149:983220
Mlinar, Hanja
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Mlinar, H. (2020). Sinteza i strukturna karakterizacija novih derivata benztiazola (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:983220

Mlinar, Hanja. "Sinteza i strukturna karakterizacija novih derivata benztiazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2020. https://urn.nsk.hr/urn:nbn:hr:149:983220

Mlinar, Hanja. "Sinteza i strukturna karakterizacija novih derivata benztiazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2020. https://urn.nsk.hr/urn:nbn:hr:149:983220

Mlinar, H. (2020). 'Sinteza i strukturna karakterizacija novih derivata benztiazola', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 29 March 2025, https://urn.nsk.hr/urn:nbn:hr:149:983220

Mlinar H. Sinteza i strukturna karakterizacija novih derivata benztiazola [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2020 [cited 2025 March 29] Available at: https://urn.nsk.hr/urn:nbn:hr:149:983220

H. Mlinar, "Sinteza i strukturna karakterizacija novih derivata benztiazola", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:149:983220

Metadata
TitleSinteza i strukturna karakterizacija novih derivata benztiazola
Title (english)Synthesis and structural characterization of novel benzothiazole derivatives
AuthorHanja Mlinar
MentorTatjana Gazivoda Kraljević (mentor)
Committee memberTatjana Gazivoda Kraljević (predsjednik povjerenstva)
Committee memberSilvana Raić-Malić (član povjerenstva)
Committee memberDragana Mutavdžić Pavlović (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2020-09-23, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
U ovom radu opisana je sinteza novih derivata benzotiazola primjenom mikrovalovima potpomognutih, mehanokemijskih i klik reakcija. Za sintezu derivata benzotiazola pripravljen je 4-O-propargilbenzaldehid (1) SN2 reakcijom 4-hidroksibenzaldehida i propargil-bromida uz K2CO3 kao bazu. 2-(4-(prop-2-in-1-iloksi)fenil)benzotiazol (2) priređen je ciklizacijom 4-O-propargilbenzaldehida (1) i 2-aminotiofenola u dimetilformamidu uz Na2S2O5 kao oksidacijsko sredstvo. Huisgenovom 1,3-dipolarnom... More cikloadicijom 2-(4-(prop-2-in-1-iloksi)fenil)benzotiazola (2) i odgovarajućih azida uz bakrov(II) acetat kao katalizator sintetizirani su 1,2,3-triazolni derivati benzotiazola (3-9). Mehanokemijske reakcije ciljanih derivata benzotiazola (3-9) provedene su u kugličnom mlinu. 1H i 13C-NMR spektroskopijom potvrđene su strukture svih novopripravljenih derivata benzotiazola. Less
Abstract (english)
This paper describes the synthesis of new benzothiazole derivatives using microwaveassisted, mechanochemical and click reactions. For the synthesis of benzothiazole derivatives, 4-O-propargylated benzaldehyde (1) was prepared by SN2 reaction of 4-hydroxybenzaldehyde and propargyl bromide using K2CO3 as a base. 2-(4-(prop-2-yn-1-yloxy)phenyl) benzothiazole (2) was prepared by cyclization reaction of 4-O-propargyl benzaldehyde (1) and 2-aminothiophenol in dimethylformamide with... More Na2S2O5 as oxidizing agent. 1,2,3-triazolyl derivatives of benzothiazole (3-9) were prepared by Huisgen 1,3-dipolar cycloaddition of 2-4-(prop-2-yn-1-yloxy)phenyl benzothiazole (2) and the corresponding azides using copper(II) acetate as catalyst. Mechanochemical reactions of the desired compounds (3-9) were performed in a ball mill. The structures of all newly prepared benzothiazole derivatives were confirmed by 1H and 13C-NMR spectroscopy. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:983220
ProjectNumber: IP-2018-01-4682
Title: Novi spojevi temeljeni na bioizosterima purina za ispitivanje njihovih antitumorskih i antipatogenih djelovanja
Acronym: PurBioCaPa
Leader: Silvana Raić-Malić
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2025-10-01
Terms of useLicence In copyright icon
Created on2023-05-08 08:11:02
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