prikaz prve stranice dokumenta N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala
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undergraduate thesis
N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. urn:nbn:hr:149:802492
Hmelina, Karla
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Hmelina, K. (2019). N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:802492

Hmelina, Karla. "N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. https://urn.nsk.hr/urn:nbn:hr:149:802492

Hmelina, Karla. "N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. https://urn.nsk.hr/urn:nbn:hr:149:802492

Hmelina, K. (2019). 'N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:802492

Hmelina K. N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2019 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:802492

K. Hmelina, "N,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:149:802492

Metadata
TitleN,N-ditriazolil-heteroaril supstituirani derivati anilina u koordiniranju iona metala
Title (english)N,N-ditriazolyl-heteroaryl substituted aniline derivatives in metal ion coordination
AuthorKarla Hmelina
MentorSvjetlana Krištafor (mentor)
Committee memberSvjetlana Krištafor (predsjednik povjerenstva)
Committee memberLidija Furač (član povjerenstva)
Committee memberMarijana Hranjec (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2019-09-16, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Cilj rada je click reakcijama pripraviti nove N,N-disupstituirane derivate anilina i odabranih heteroaromatskih jezgri međusobno povezanih 1,2,3-triazolnim prstenom. Click reakcijom pripravljeni 1,2,3-triazolni prsten je zbog svog dipolnog karaktera i prisutnosti dušikovih atoma sa slobodnim elektronskim parovima česta struktura u koordiniranju metalnih kationa. Sinteza željenih derivata je provedena u tri koraka, gdje su u prvom koraku, pripravljeni N-mono- i N,N-dipropargilirani derivati anilina. U drugom koraku su iz anilina, 7-amino-4-metilkumarina i 2-aminobenztiazola pripremljeni odgovarajući aromatski azidi reakcijom nukleofilne supstitucije s natrijevim azidom u prisutnosti natrijeva nitrita. Konačni spojevi pripremljeni su u trećem koraku click reakcijama između alkina i odgovarajućih aromatskih azida, a strukture dobivenih spojeva potvrđene su 1H i 13C NMR spektroskopijom. Nadalje, provjerena je potencijalna primjena sintetiziranog N,N-bis((1-fenil-1H-1,2,3-triazol-4-il)metil)anilina (5) kao kemosenzora ispitivanjem spektralnih karakteristika u prisutnosti metalnih iona UV-vidljivom spektroskopijom. Za ispitivanje utjecaja metalnih kationa, u pripravljenu otopinu spoja 5 dodavan je određeni alikvot otopine metalnih kationa u omjeru spoj: metalni ion = 1:1 i 1:5.
Abstract (english)
The aim of this work was to prepare the new N,N-disubstituted aniline and heteroaryl derivatives linked by a 1,2,3-triazole ring using click reactions. The 1,2,3-triazole ring generated by the click reaction is a common motif in metal ion coordination chemistry, due to its dipole character and the presence of nitrogen atoms with free electron pairs. The synthesis was carried out in three steps. In the first step N-mono- and N,N-dipropargylated aniline derivatives were prepared. In the second step, the corresponding aromatic azides were prepared from aniline, 7-amino-4-methylcoumarin and 2-aminobenzthiazole by nucleophilic substitution with sodium azide in the presence of sodium nitrite. The target compounds were prepared by click reactions of alkynes and corresponding azides. The structures of the newly prepared compounds were confirmed by 1H and 13C NMR spectroscopy. Furthermore, the potential application of N,N-bis((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)aniline (5) as chemosensor for metal ions was evaluated by UV–Vis spectroscopy. To test the influence of metal cations on spectral properties of compound 5, absorption spectra of 5 in presence of metal ions (1.0 and 5.0 equivalents) were recorded.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:802492
ProjectNumber: IP-2014-09-3386
Title: Dizajn i sinteza novih dušikovih heterocikličkih fluorofora i fluorescentnih nanomaterijala kao kemijskih senzora za pH i metalne ione
Title: Design and Synthesis of Novel Nitrogen-Containing Heterocyclic Fluorophores and Fluorescent Nanomaterials for pH and Metal-Ion Sensing
Acronym: iNFiNiTE–SENS
Leader: Robert Vianello
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Chemical Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka kemijskog inženjerstva)
Type of resourceText
File originBorn digital
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Created on2023-05-23 12:33:11