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undergraduate thesis
"One-pot" sinteza novih derivata benztiazola
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. urn:nbn:hr:149:888216
Žuža, Nika
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Žuža, N. (2019). "One-pot" sinteza novih derivata benztiazola (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:888216

Žuža, Nika. ""One-pot" sinteza novih derivata benztiazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. https://urn.nsk.hr/urn:nbn:hr:149:888216

Žuža, Nika. ""One-pot" sinteza novih derivata benztiazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2019. https://urn.nsk.hr/urn:nbn:hr:149:888216

Žuža, N. (2019). '"One-pot" sinteza novih derivata benztiazola', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:888216

Žuža N. "One-pot" sinteza novih derivata benztiazola [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2019 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:888216

N. Žuža, ""One-pot" sinteza novih derivata benztiazola", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:149:888216

Metadata
Title"One-pot" sinteza novih derivata benztiazola
Title (english)"One-pot" synthesis of novel benzothiazole derivatives
AuthorNika Žuža
MentorTatjana Gazivoda Kraljević (mentor)
Committee memberTatjana Gazivoda Kraljević (predsjednik povjerenstva)
Committee memberAndrijana Meščić Macan (član povjerenstva)
Committee memberDajana Kučić Grgić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2019-07-04, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
U ovom radu opisana je „one-pot“ sinteza 6-(4-aril/alikl-1,2,3-triazolil)-2-arilbenztiazola, u jednoj reakcijskoj posudi bez izolacije međuprodukata. 6-azido derivati benztiazola nastaju in situ reakcijom 6-amino-2-arilbenztiazola s tert-butilnitritom i TMSN3. Klik reakcijom kataliziranom bakrom nastalih 6-azidobenztiazola i odgovarajućih terminalnih alkina priređeni su derivati benztiazola supstituirani u položaju 2 arilnim supstituentom i 4-supstituiranim 1,2,3-triazolnim prstenom u položaju 6. Strukture svih novopriravljenih spojeva potvrđene su 1H-NMR spektroskopijom.
Abstract (english)
This paper describes "one- pot" synthesis of 6-(4-aryl/alkyl-1,2,3-triazolyl)-2-arylbenzothiazole in one reaction vessel without isolation of the intermediates. 6-azido benzothiazole derivatives are synthesized in situ by reaction of 6-amino-2-arylbenzothiazole with tert-butylnitrite and TMSN3. Copper catalyzed click reaction of 6-azidobenzothiazole and corresponding terminal alkynes gave benzothiazole derivatives substituted at position 2 with aryl substituents and with 4-substituted 1,2,3-triazole ring at position 6. The structures of all novel compounds were confirmed by 1H-NMR spectroscopy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:888216
ProjectNumber: IP-2018-01-4682
Title: Novi spojevi temeljeni na bioizosterima purina za ispitivanje njihovih antitumorskih i antipatogenih djelovanja
Acronym: PurBioCaPa
Leader: Silvana Raić-Malić
Jurisdiction: Croatia
Funder: HRZZ
Funding stream: IP
Study programmeTitle: Environmental Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka ekoinženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka ekoinženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2023-05-29 13:36:25