prikaz prve stranice dokumenta Mikrobna razgradnja ksenobiotika u aerobnim uvjetima
Embargo period 2026-10-01
master's thesis
Mikrobna razgradnja ksenobiotika u aerobnim uvjetima
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. urn:nbn:hr:149:022141
Muzica, Katarina
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Muzica, K. (2023). Mikrobna razgradnja ksenobiotika u aerobnim uvjetima (Master's thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:022141

Muzica, Katarina. "Mikrobna razgradnja ksenobiotika u aerobnim uvjetima." Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:149:022141

Muzica, Katarina. "Mikrobna razgradnja ksenobiotika u aerobnim uvjetima." Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:149:022141

Muzica, K. (2023). 'Mikrobna razgradnja ksenobiotika u aerobnim uvjetima', Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 26 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:022141

Muzica K. Mikrobna razgradnja ksenobiotika u aerobnim uvjetima [Master's thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2023 [cited 2024 December 26] Available at: https://urn.nsk.hr/urn:nbn:hr:149:022141

K. Muzica, "Mikrobna razgradnja ksenobiotika u aerobnim uvjetima", Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:149:022141

Metadata
TitleMikrobna razgradnja ksenobiotika u aerobnim uvjetima
Title (english)Microbial degradation of xenobiotics under aerobic conditions
AuthorKatarina Muzica
MentorMarija Vuković Domanovac (mentor)
Committee memberMarija Vuković Domanovac (predsjednik povjerenstva)
Committee memberZvjezdana Findrik Blažević (član povjerenstva)
Committee memberMonika Šabić Runjavec (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2023-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Chemical Engineering
Abstract
Mnoga znanstvena otkrića omogućila su bolju kvalitetu života i dovela do povećane proizvodnje ksenobiotika koji se najčešće nepravilno odlažu te su jedan od glavnih uzročnika loše kakvoće okoliša. Značajna skupina takvih tvari antropogenog podrijetla su farmaceutici. Kako oni imaju složenu strukturu i mehanizam djelovanja na različite vrste organizama, važno je pronaći nove i učinkovite načine uklanjanja ksenobiotika te pratiti njihov utjecaj na okoliš. U tu svrhu se sve više koriste ekonomični i okolišno prihvatljivi procesi poput biorazgradnje, koji koristi enzimske i metaboličke sposobnosti mikroorganizama za razgradnju organskih onečišćujućih tvari. U ovome radu proveden je proces biorazgradnje β-laktamskog antibiotika amoksicilina pomoću okolišne Gram-pozitivne bakterije Bacillus subtilis. Biorazgradnja amoksicilina provedena je u šaržnim i aerobnim uvjetima. Početne koncentracije amoksicilina iznosile su 278 mg L^-1 (Bs-1) i 658 mg L^-1 (Bs-2). Na temelju rezultata testova osjetljivosti, aktivnost bakterijske kulture Bacillus subtilis nije inhibirana djelovanjem navedenog antibiotika. Učinkovitost procesa biorazgradnje amoksicilina iznosila je 99,7 %.
Abstract (english)
Many scientific discoveries have enabled a better quality of life and led to increased production of xenobiotics, most of which are improperly disposed of and are a major cause of poor environmental quality. An important group of such substances of anthropogenic origin are pharmaceuticals. Since they have a complex structure and mechanism of action on different types of organisms, it is important to find new and effective methods for disposing of xenobiotics and monitoring their impact on the environment. To this end, economical and environmentally sound methods such as biodegradation, which utilises the enzymatic and metabolic capabilities of microorganisms to degrade organic pollutants, are increasingly being used. In this work, the process of biodegradation of the β-lactam antibiotic amoxicillin was carried out using the environmentally occurring Gram-positive bacterium Bacillus subtilis. The biodegradation of amoxicillin was carried out in a batch process and under aerobic conditions. The initial concentrations of amoxicillin were 278 mg L^-1 (Bs-1) and 658 mg L^-1 (Bs-2). According to the results of the susceptibility tests, the activity of the Bacillus subtilis bacterial culture was not affected by the mentioned antibiotic. The efficiency of the biodegradation process of amoxicillin was 99.7 %.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:022141
Study programmeTitle: Environmental Engineering - Graduate study
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka ekoinženjerstva (magistar/magistra inženjer/inženjerka ekoinženjerstva)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2026-10-01
Terms of useLicence In copyright icon
Created on2023-07-27 10:45:21