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master's thesis
Monitoring of AOP degradation of selected pharmaceutical
Zagreb, Split: University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. urn:nbn:hr:149:077137
Krpina, Ana
University of Zagreb
Faculty of Chemical Engineering and Technology
University of Split
Faculty of Chemistry and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Krpina, A. (2023). Monitoring of AOP degradation of selected pharmaceutical (Master's thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:077137

Krpina, Ana. "Monitoring of AOP degradation of selected pharmaceutical." Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology; University of Split, Faculty of Chemistry and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:149:077137

Krpina, Ana. "Monitoring of AOP degradation of selected pharmaceutical." Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology; University of Split, Faculty of Chemistry and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:149:077137

Krpina, A. (2023). 'Monitoring of AOP degradation of selected pharmaceutical', Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology; University of Split, Faculty of Chemistry and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:077137

Krpina A. Monitoring of AOP degradation of selected pharmaceutical [Master's thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; Split: University of Split, Faculty of Chemistry and Technology; 2023 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:077137

A. Krpina, "Monitoring of AOP degradation of selected pharmaceutical", Master's thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb; University of Split, Faculty of Chemistry and Technology, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:149:077137

Metadata
TitleMonitoring of AOP degradation of selected pharmaceutical
Title (croatian)Praćenje razgradnje odabranih farmaceutika naprednim oksidacijskim procesima
AuthorAna Krpina
MentorŠime Ukić (mentor)
Committee memberŠime Ukić (predsjednik povjerenstva)
Committee memberMatija Cvetnić (član povjerenstva)
Committee memberLidija Furač (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
GranterUniversity of Split
Faculty of Chemistry and Technology
Split
Defense date and country2023-07-18, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Pharmaceuticals are extensively utilized globally and their persistent nature and potential adverse impacts on the environment and human health are well−documented. The ubiquitous usage of pharmaceuticals significantly contributes to water pollution which has become a major global issue. Advanced oxidation processes have emerged as a promising solution to address this problem. In our study, we focused on monitoring the degradation of a commonly used active pharmaceutical compound, pantoprazole, using UV/H2O2 and UV/S2O82– advanced oxidation processes. We studied the influence of various water matrix factors, including pH, oxidant concentration, phosphate ion, sulfate ion, chloride ion, nitrite ion, nitrate ion, and humic acid, on the degradation rates of pantoprazole. To ensure efficient data collection while minimizing the experimental runs, we used the Taguchi design of experiment. The experimental results were analyzed using statistical software MiniTab. The analysis emphasized the notable influences of water matrix constituents on the degradation rates, which in most cases, were in agreement with previous scientific findings.
Abstract (croatian)
Farmaceutici se uvelike koriste na globalnoj razini, a njihova trajna priroda i potencijalni štetni utjecaji na okoliš i ljudsko zdravlje dobro su dokumentirani. Sveprisutna uporaba farmaceutika značajno pridonosi onečišćenju vode koje je postalo veliki globalni problem. Napredni oksidacijski procesi pojavili su se kao obećavajuće rješenje za rješavanje ovog problema. U ovom radu smo se usredotočili na praćenje razgradnje često korištenog aktivnog farmaceutskog spoja, pantoprazola, korištenjem UV/H2O2 i UV/S2O82– naprednih oksidacijskih procesa. Proučavali smo utjecaj različitih čimbenika vodene matrice, uključujući pH, koncentraciju oksidansa, fosfatni ion, sulfatni ion, kloridni ion, nitritni ion, nitratni ion i huminsku kiselinu, na brzinu razgradnje pantoprazola. Kako bismo osigurali učinkovito prikupljanje podataka uz minimiziranje broja eksperimenata, upotrijebili smo Taguchijev dizajn eksperimenta. Eksperimentalni rezultati analizirani su pomoću statističkog programa MiniTab. Analiza je naglasila značajne utjecaje sastojaka vodene matrice na brzinu razgradnje, koji su u većini slučajeva bili u skladu s prethodnim znanstvenim spoznajama.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:149:077137
Study programmeTitle: Chemical and environmental technology - graduate - university
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka kemijskog inženjerstva (magistar/magistra inženjer/inženjerka kemijskog inženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-07-27 14:28:28