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undergraduate thesis
Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. urn:nbn:hr:149:978432
Grubišić, Karlo
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Grubišić, K. (2023). Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:978432

Grubišić, Karlo. "Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:149:978432

Grubišić, Karlo. "Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:149:978432

Grubišić, K. (2023). 'Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 25 August 2024, https://urn.nsk.hr/urn:nbn:hr:149:978432

Grubišić K. Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2023 [cited 2024 August 25] Available at: https://urn.nsk.hr/urn:nbn:hr:149:978432

K. Grubišić, "Utjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:149:978432

Metadata
TitleUtjecaj temperature na elektrokemijsku reakciju ciklizacije N-benzilamida i N-benziltioamida
Title (english)The influence of temperature on the electrochemical cyclization reaction of N-benzylamides and N-benzylthioamides
AuthorKarlo Grubišić
MentorIrena Škorić (mentor)
MentorGoran Kragol (komentor)
Committee memberIrena Škorić (predsjednik povjerenstva)
Committee memberKristina Tolić Čop (član povjerenstva)
Committee memberGoran Kragol (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2023-09-22, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Različiti derivati 4H-1,3-benzotiazina i 4H-1,3-benzoksazina zadnjih se godina intenzivno proučavaju zbog svog potencijalnog farmakološkog djelovanja. Način njihove sinteze, ali i sinteze drugih organskih molekula, sve se više okreće ka elektrokemijskoj metodi koja prednjači kada je u pitanju ekonomičnost i ekološka prihvatljivost. U ovom je radu korištena metoda elektrokemijske dehidrogenativne ciklizacije za sintezu halogeniranih derivata navedenih spojeva, pri čemu su uspješno izolirani spojevi 6a, 6a', 6b i 7a'. Praćen je utjecaj temperature, ali i drugih čimbenika, na uspješnost reakcije. Struktura svih dobivenih spojeva potvrđena je 1H-NMR spektroskopskom metodom, a mase spojeva detektirane su na UPLC-MS/UV uređaju.
Abstract (english)
In recent years, different derivatives of 4H-1,3-benzothiazine and 4H-1,3-benzoxazine have been extensively studied due to their potential pharmacological activity. The method of their synthesis, as well as the synthesis of other organic molecules, is increasingly shifting towards electrochemical methods, which excel in terms of cost-effectiveness and environmental friendliness. In this study, an electrochemical dehydrogenative cyclization method was employed for the synthesis of halogenated derivatives of the previously mentioned compounds, resulting in the successful isolation of compounds 6a, 6a', 6b, and 7a'. The influence of temperature, among other factors, on the success of the reaction was monitored. The structure of all obtained compounds was confirmed using the 1H-NMR spectroscopic method, and the masses of the compounds were detected using a UPLC-MS/UV device.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:978432
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2023-11-30 17:46:58