prikaz prve stranice dokumenta Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola
Embargo period 2026-09-01
undergraduate thesis
Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2024. urn:nbn:hr:149:862832
Škrtić, Jelena
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Škrtić, J. (2024). Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:862832

Škrtić, Jelena. "Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2024. https://urn.nsk.hr/urn:nbn:hr:149:862832

Škrtić, Jelena. "Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2024. https://urn.nsk.hr/urn:nbn:hr:149:862832

Škrtić, J. (2024). 'Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:862832

Škrtić J. Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2024 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:862832

J. Škrtić, "Spektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:149:862832

Metadata
TitleSpektrofotometrijsko određivanje konstante ionizacije analoga rezveratrola
Title (english)Spectrophotometric determination of ionisation constant of resveratrol analogues
AuthorJelena Škrtić
MentorSandra Babić (mentor)
Committee memberSandra Babić (predsjednik povjerenstva)
Committee memberIrena Škorić (član povjerenstva)
Committee memberLidija Furač (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2024-09-03, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Poznavanje konstante ionizacije (Ka) izuzetno je važno prilikom razvoja novih lijekova s obzirom da nam omogućuje predviđanje ponašanja lijekova u fiziološkim uvjetima. Također, ima važnu ulogu kod određivanja ADMET (apsorpcija, distribucija, metabolizam, izlučivanje, toksičnost) svojstava lijekova. Vrijednosti pKa moguće je odrediti različitim metodama poput potenciometrije, kapilarne elektroforeze, tekućinske kromatografije te UV/VIS spektrofotometrije. U ovom radu određene su pKa vrijednosti novih analoga rezveratrola UV/VIS spektrofotometrijskom metodom. Eksperimentalno određene pKa vrijednosti iznose: 9.80±0.09, 9.94±0.14, 9.10±0.05, 9.44±0.04 i 9.58±0.16.
Abstract (english)
The knowledge of ionisation constant (Ka) is extremly important for the development of new drugs as it allows us to predict the behavior of drugs under psysiological conditions. It also plays a crucial role in determinig the ADMET (absorption, distribution, metabolism, excretion, toxicity) prosperties of drugs. The pKa values can be determined using various methods such as potentiometry, capillary electrophoresis, liquid chromatography, and UV/VIS spectrophotometry. In this study, the pKa values of new resveratrol analogs were determined using the UV/VIS spectrophotometric method. The experimentally determined pKavalues are: 9.80±0.09, 9.94±0.14, 9.10±0.05, 9.44±0.04 and 9.58±0.16.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:862832
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Advanced materials and technologies
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2026-09-01
Terms of useLicence In copyright icon
Created on2024-10-14 09:54:57