The purpose of this work was to simulate the pycnometric density determination of samples with weighing measurement errors. By processing simulated data, the density of given samples (resin, glass, and titanium) was determined and compared with the known actual density to assess the impact of different parameters on the overall error in density determination. All data were processed in Excel, and the calculation was divided into three parts. In the first part, the influence of the sample's density was monitored, then in the second part, the impactof the measuring liquid's density was observed, and finally, the effect of the volume ratio between the sample and the pycnometer was analyzed. For each section, relative and absolute errors were calculated, and the final data were presented in tables and graphs to make results clearer. From the error values, it was possible to observe which sample and which measuring liquid caused the largest deviations. In conclusion, the largest deviation always occurred with the titanium sample, regardless of the changed parameters. Testing the data shows that the results obtained using the pycnometer method for determining the sample density will, in most cases, yield values very close to the theoretical ones, making this method highly useful. It is advisable to use a measuring liquid whose density is close to that of the substance being measured, and the error decreases with an increase in the amount of sample in the pycnometer.