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undergraduate thesis
'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. urn:nbn:hr:149:197196
Krošl, Ivona
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Krošl, I. (2016). 'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:197196

Krošl, Ivona. "'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:149:197196

Krošl, Ivona. "'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:149:197196

Krošl, I. (2016). ''Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 04 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:197196

Krošl I. 'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2016 [cited 2024 November 04] Available at: https://urn.nsk.hr/urn:nbn:hr:149:197196

I. Krošl, "'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:149:197196

Metadata
Title'Click' reakcijom do novih kumarinskih derivata 1,2,3-triazola
Title (english)The novel coumarin derivatives of 1,2,3-triazole derivatives via click reaction
AuthorIvona Krošl
MentorSilvana Raić-Malić (mentor)
Committee memberSilvana Raić-Malić (predsjednik povjerenstva)
Committee memberTatjana Gazivoda Kraljević (član povjerenstva)
Committee memberSanja Martinez (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2016-07-08, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Organic Chemistry
Abstract
Cilj ovog rada bila je sinteza novih biološki aktivnih 1,4-disupstituiranih derivata kumarina i 1,2,3-triazola. 4-Klormetilni kumarinski derivati s hidroksi i metoksi supstituentima u poloţaju 6 ili 7 kumarinskog prstena priređeni su Pechmanovom ciklizacijom koji su zatim prevedeni nukleofilnom supstitucijom u azidne derivate, kao ključne prekursore,. Hibridi kumarina i 1,2,3-triazola pripravljeni su Huisgenovom 1,3- dipolarnom cikloadicijom terminalnih alkina i kumarinskih azida kataliziranom bakrom pomoću mikrovalnog zračenja. Strukture svih priređenih spojeva potvrđene su 1H i 13C NMR spektroskopijom. Provedena su antioksidativna ispitivanja priređenih spojeva metodom cikličke voltametrije.
Abstract (english)
The aim of this work was the synthesis of novel 1,4-disubstituted 1,2,3-triazole coumarin derivatives with potential biological activity. 4-Chloromethyl coumarin derivatives with hydroxyl and methoxyl substituents at the positions 6 or 7 of the coumarin ring were prepared by the Pechmann reaction and converted to the corresponding azides, as key precursors. Hybrids of coumarin and 1,2,3-triazoles were prepared by the copper catalyzed Huisgen 1,3-dipolar cycloaddition between terminal alkynes and coumarin azide using microwave irradiation. The structures of all synthesized compounds were confirmed by 1H and 13C NMR spectroscopy. Antioxidant properties of the prepared compounds were investigated by using cyclic voltammetry.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:197196
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-12-05 08:39:25