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undergraduate thesis
Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. urn:nbn:hr:149:979198
Beč, Anja
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Beč, A. (2016). Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:979198

Beč, Anja. "Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:149:979198

Beč, Anja. "Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:149:979198

Beč, A. (2016). 'Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 04 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:979198

Beč A. Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2016 [cited 2024 November 04] Available at: https://urn.nsk.hr/urn:nbn:hr:149:979198

A. Beč, "Sinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:149:979198

Metadata
TitleSinteza biološki aktivnih cikličkih derivata 5(6)-amino supstituiranih benzimidazola
Title (english)Synthesis of biologically active cyclic derivatives of 5(6)-amino substituted benzimidazoles
AuthorAnja Beč
MentorMarijana Hranjec (mentor)
Committee memberMarijana Hranjec (predsjednik povjerenstva)
Committee memberNataša Perin (član povjerenstva)
Committee memberLidija Furač (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2016-09-09, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Organic Chemistry
Abstract
U okviru ovog rada provedena je sinteza acikličkog 2-benzimidazolil supstituiranog akrilonitrila 6 te njegovog cikličkog analoga benzimidazo[1,2-a]kinolina 7. Spojevi su priređeni klasičnim reakcijama organske sinteze te aminacijom potpomognutom mikrovalnim zračenjem. Benzimidazolil-supstituirani akrilonitril 6 priređen iz 2-cijanometil-5(6)- piperidinilbenzimidazola 4 i o-klorbenzaldehida 5, dok je benzimidazo[1,2-a]kinolin 7 priređen termičkom ciklizacijom akrilonitrila 6 u sulfolanu pri čemu je dobivena smjesa dva regioizomera. Strukture priređenih spojeva potvrđene su 1H i 13C NMR spektroskopijom. Spojevi 3-7 okarakterizirani su UV/Vis i fluormetrijskom spektroskopijom.
Abstract (english)
This work presents the synthesis of novel 2-benzimidazolyil-substituted acrylonitrile 6 and it's cyclic analog, benzimidazo[1,2-ɑ]qinoline 7. Novel compounds were prepared by using a classical reactions of organic chemistry and microwave assisted amination. Benzimidazolyilsubstituted acrylonitrile 6 was prepared in reaction of 2-cyanomethyl-5(6)- piperidinylbenzimidazole 4 with o-chlorobenzaldehyde 5. Benzimidazo[1,2-ɑ]quinoline 7 was prepared by thermal cyclization of acrylonitrile 6 in sulfolane as a mixture of two regioisomers. The structures of all compounds were determined by means of 1H and 13C NMR and UV/Vis and fluorimetric spectroscopy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:979198
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2018-02-02 12:49:54