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undergraduate thesis
Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. urn:nbn:hr:149:345988
Gulin, Marjana
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Gulin, M. (2016). Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:345988

Gulin, Marjana. "Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:149:345988

Gulin, Marjana. "Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:149:345988

Gulin, M. (2016). 'Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 20 December 2024, https://urn.nsk.hr/urn:nbn:hr:149:345988

Gulin M. Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2016 [cited 2024 December 20] Available at: https://urn.nsk.hr/urn:nbn:hr:149:345988

M. Gulin, "Sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:149:345988

Metadata
TitleSinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina
Title (english)Synthesis and spectroscopic characterization of novel 2-amido substituted benzimidazo[1,2-a]quinolines
AuthorMarjana Gulin
MentorMarijana Hranjec (mentor)
Committee memberMarijana Hranjec (predsjednik povjerenstva)
Committee memberIrena Sović (član povjerenstva)
Committee memberŠime Ukić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2016-09-20, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Organic Chemistry
Abstract
U ovom radu opisana je sinteza i spektroskopska karakterizacija novih 2-amido supstituiranih benzimidazo[1,2-a]kinolina. Novi spojevi priređeni su klasičnim reakcijama organske sinteze. Aciklički prekursor E-2-[2-(p-cijanofenil)etenil]benzimidazol 3 pripravljen je iz 2- metilbenzimidazola i 4-cijanobenzaldehida. Fotokemijskom ciklizacijom etanolne otopine spoja 3 dobiven je 2-cijanobenzimidazo[1,2-a]kinolin 4. Iz cijano supstituiranog derivata 4 u kiseloj vodenoj otopini priređena je benzimidazo[1,2-a]kinolin-2-karboksilna kiselina 5 koja u reakciji sa SOCl2 daje glavni prekursor za sintezu amida, benzimidazo[1,2-a]kinolin-2- karbonil-klorid 6. 2-amido supstituirani benzimidazo[1,2-a]kinolini 7-9 dobiveni su reakcijom benzimidazo[1,2-a]kinolin-2-karbonil-klorida 6 s odgovarajućim aminima. Strukture novopriređenih spojeva okarakterizirane su UV/Vis i fluorimetrijskom spektroskopijom, te su potvrđene 1H i 13C NMR spektroskopijom.
Abstract (english)
This work presents the synthesis and spectroscopic characterization of novel 2-amido substituted benzimidazol[1,2-a]quinolines. Novel compounds were prepared by classical reactions of organic chemistry. Acyclic precursor E-2-[2-(p-cyanophenyl)etenyl]benzimidazol 3 was prepared from 2-metylbenzimidazole and 4-cyanobenzaldehyde. 2-cyanobenzimidazo[ 1,2-a]quinoline 4 was prepared by photochemical cyclization of ethanolic solution of compound 3. Benzimidazo[1,2-a]quinoline-2-carboxylic acid 5 was prepared by acidic hydrolysis from compound 4. In the reaction of carboxylic acid 5 with SOCl2 the corresponding benzimidazo[1,2-a]quinoline-2-carbonylchloride 6 as a main precursor for the synthesis of targeted amides, was prepared. 2-amido substituted benzimidazo[1,2-a]quinolines 7-9 are were obtained in the reaction with corresponding amines. All newly prepared compounds were characterized by UV/Vis and fluorimetric spectroscopic, while the structures were confirmed by means of 1H i 13C NMR spectroscopy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:345988
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2018-02-08 13:47:06