The analysis of alloys, as well as any other chemical analysis begins by sampling. Sampling methods of alloy mainly include destructive methods such as turning, boring and cutting, and obtained pieces of alloy dissolve in strong inorganic acids. Solutions of such samples are commonly analyzed by atomic absorption spectrometry (AAS) or optical emission spectrometry with inductively on coexcitation in the plasma (ICP-OES). In cases of limited amounts of samples of alloys or in situations where destructive sampling of the alloy is not desirable, we are reaching out to non-destructive methods of chemical analysis and sampling, and one of these methods is the method of anodic sampling or microdestructive anodic dissolution of the sample surface. A method of sampling an anode is usually associated with thin-layer chromatography as a method of chemical analysis. The aim of this study was to analyze alloy of archaeological significance, found in the sea. The analysis which was preceded by anodic sampling is carried out by thin-layer chromatography. In addition to the analysis, an optimum developer for the separation of the components of lead alloys was determined, such as sampling conditions anode, electrolyte for sampling, and time applying the sample to the chromatography medium. The analysis determined certain major components of the alloy, which is consistent with previously conducted destructive, spectrometric analysis of the alloy composition. For the most part it consists of lead and tin. Spectrometric method gives more accurate results of the analysis, but unlike the thin-layer chromatography takes more time due to the sample preparation and expensive equipment. Thin-layer chromatography is an excellent method as a preliminary with the main advantage of anodic sampling, but it is not possible to determine the minor component and trace elements.