prikaz prve stranice dokumenta Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida
  Download
PDF 1.96 MB
undergraduate thesis
Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2017. urn:nbn:hr:149:052248
Lojan, Petra
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

Cite this document

Lojan, P. (2017). Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:052248

Lojan, Petra. "Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2017. https://urn.nsk.hr/urn:nbn:hr:149:052248

Lojan, Petra. "Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2017. https://urn.nsk.hr/urn:nbn:hr:149:052248

Lojan, P. (2017). 'Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:052248

Lojan P. Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2017 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:149:052248

P. Lojan, "Sinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:149:052248

Metadata
TitleSinteza i strukturna karakterizacija ferocen-izokinolinskih hibrida
Title (english)Synthesis and structural characterization of ferrocene-isoquinoline hybrids
AuthorPetra Lojan
MentorTatjana Gazivoda Kraljević (mentor)
Committee memberTatjana Gazivoda Kraljević (predsjednik povjerenstva)
Committee memberMarijana Kraljić Roković (član povjerenstva)
Committee memberAndrijana Meščić Macan (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2017-07-10, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Organic Chemistry
Abstract
U ovom radu opisana je sinteza novih derivata izokinolina i ferocen-izokinolinskog hibrida te njihova strukturna karakterizacija. Reakcijom ciklizacije potpomognutom mikrovalnim zračenjem 2-klorbenzaldehida i odgovarajućih terminalnih alkina sintetizirani su derivati izokinolina supstituirani u položaju 3 alkilnim lancima (1-3). Reakcijom bromiranja izokinolina NBS-om uveden je u položaj 5 izokinolinskog prstena pri -25 °C, koji je potom preveden u 5- azidoizokinolin (5) s NaN3. Mikrovalnim zračenjem potpomognutom „klik“ reakcijom 5- azidoizokinolina s etinilferocenom uz Cu katalizator pripravljen je 4-ferocenil–1,2,3-triazolizokinolinski hibrid (6). Strukturna karakerizacija derivata izokinolina provedena je 1H NMR spektroskopijom.
Abstract (english)
Synthesis and structural characterization of novel isoquinoline derivatives and a ferrocene- isoquinoline hybrid were described in this paper. Microwave assisted cyclization of 2-chlorobenzaldehyde with corresponding terminal alkynes gave isoquinoline derivatives substituted at position 3 with alkyl side chain (1-3). 5-Bromoisoquinoline was prepared by bromination reaction of isoquinoline with NBS at -25 °C, which was converted to 5-azido isoquinoline (5) with NaN3. 4-Ferrocenyl–1,2,3-triazole-isoquinoline hybrid (6) was synthesized by microwave assisted „klik“ reaction of 5-azido isoquinoline with ethynylferrocene in the presence of Cu as catalyst. Structural characterization of novel isoquinoline derivatives was performed by 1H NMR spectroscopy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:052248
Study programmeTitle: Applied Chemistry - Undergraduate study; specializations in: Environmental chemistry and green technologies, Advanced materials and technologies, Applied organic chemistry
Course: Applied organic chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) primijenjene kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-01-05 11:50:07