The goal of pharmaceutical studies is to keep equable content of active pharmaceutical ingredient in tablets in order to enhance their quality and properties and to reduce production costs. The homogeneity of preparation includes homogeneity of mass and uniformity of the content. Determination of the content of active ingredient in each tablet is carried out in order to control the quality of the preparation and its stability. The tablet should release the active ingredient to the desired location at a correct dose, optimum time and reduce side effects, so testing the release rate of the active ingredient is one of the major tests to characterize the preparation. In conventional methods for testing the release of the active ingredient from oral forms, the composition should be injected into a large volume of medium and subjected to mixing to achieve better in vivo conditions. In this paper, the study was conducted on a sample of 10 Multaq tablets. The uniformity of mass, the hardness and tablet dimensions, which include diameter and thickness, and tablet dissolution test were performed. The uniformity of the contents was tested by UV/Vis spectrophotometric method. In vitro research of the release of dronedarone from tablets was performed in the USP2 device under the prescribed conditions. The results show that there was no loss of weight during the research of tablets friability. The relative standard deviation of dronedarone content is less than 6 %, which indicates the plausibility of content variation. The obtained dronedarone release profiles are similar to those obtained on the basis of research data.