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undergraduate thesis
Kokristali u farmaceutskoj industriji
Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology, 2017. urn:nbn:hr:149:512146
Lilić, Matea
University of Zagreb
Faculty of Chemical Engineering and Technology

Institutional repository: Repository of Faculty of Chemical Engineering and Technology University of Zagreb

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Lilić, M. (2017). Kokristali u farmaceutskoj industriji (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:149:512146

Lilić, Matea. "Kokristali u farmaceutskoj industriji." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2017. https://urn.nsk.hr/urn:nbn:hr:149:512146

Lilić, Matea. "Kokristali u farmaceutskoj industriji." Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, 2017. https://urn.nsk.hr/urn:nbn:hr:149:512146

Lilić, M. (2017). 'Kokristali u farmaceutskoj industriji', Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, accessed 03 November 2024, https://urn.nsk.hr/urn:nbn:hr:149:512146

Lilić M. Kokristali u farmaceutskoj industriji [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Chemical Engineering and Technology; 2017 [cited 2024 November 03] Available at: https://urn.nsk.hr/urn:nbn:hr:149:512146

M. Lilić, "Kokristali u farmaceutskoj industriji", Undergraduate thesis, University of Zagreb, Faculty of Chemical Engineering and Technology, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:149:512146

Metadata
TitleKokristali u farmaceutskoj industriji
Title (english)Co-crystals in pharmaceutical industry
AuthorMatea Lilić
MentorJasna Prlić Kardum (mentor)
Committee memberJasna Prlić Kardum (predsjednik povjerenstva)
Committee memberAleksandra Sander (član povjerenstva)
Committee memberLidija Furač (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
Zagreb
Defense date and country2017-09-22, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Chemical Engineering
Mechanical, Thermal and Separation Processes
Abstract
Na farmaceutskom tržištu postoje lijekovi različitih oblika,sastava i namjena. Poboljšavanje njihovih fizikalno-kemijskih svojstva glavni je cilj istraživanja u farmaceutskoj industriji. Vodeći problemi jesu loša topljivost lijekova i njihova slaba bioraspoloživost, zbog kojih na tržište dospije manje od 1 % djelatnih farmaceutskih tvari. Moguće rješenje nudi se u primjeni kokristalizacije u kristalnom inženjerstvu kojom se omogućuje modificiranje i poboljšavanje fizikalno-kemijskih svojstva djelatnih farmaceutskih tvari uz istodobno zadržavanje intrizične aktivnosti i strukture molekule lijeka.
Abstract (english)
There are many drugs on pharmaceutical market characterized by different solid state, composition and purpose. Enhancement of their physicochemical properties is one of the main goals of many researches in pharmaceutical industry. Main issues are low solubility and poor bioavailability of drugs, causing that less then 1% of active pharmaceutical ingredients reaches the market. Application of co-crystallization in crystallization engineering can possibly provide solutions to these challenges by modifications and improvement of physicochemical properties of the active pharmaceutical ingredients while maintaining the intrinsic activity of the drug molecule.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:149:512146
Study programmeTitle: Environmental Engineering - Undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka ekoinženjerstva (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka ekoinženjerstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
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Created on2021-03-30 12:16:05