Water pollution, either organic, anorganic or by microorganisms is a growing problem. Also, the problem is a group of so called emerging pollutants and Priority Substances (that contain some emerging pollutants on the list), which includes pharmaceuticals. Standard waste water treatment plant (WWTP) is not adequate in terms of removal that kind of components from water, since pharmaceuticals have been detected in water even after certain kind of treatment. Hence, lately a lot of effort has been put on an investigation and developing new methods for waste water purification. One important method is chemical oxidation with some novel chemical agents, such as ferrates (VI), i.e. iron in higher oxidation state. The aim of this study was to investigate possibility of application ferrates (VI), K2FeO4, for removal of pharmaceuticals from waste water. Impact od pH value and concentration of ferrates (VI) on removal efficiency of carbamazepine from water was investigated during the proces in batch reactor with Design of Experiments and Response Surface Methodology. Concentration of carbamazepine during the process was monitored by high performance liquid chromatography. Impurities left behind after the process in a sample of carbamazepine with ferrates (VI) at optimal conditions and physico-chemical indicators such as Chemical oxigen demand, COD, and Total organic carbon, TOC, were determined. In this paper, removal rate of carbmazepine around 32,3 % is achieved. It is estimated that the pH value of solution and the concentration of ferrates (VI) have almost even level of importance and influence for the process, while the optimal pH value is 5 and concentration of ferrates (VI) is 75 mg/L.