To cope with today’s urban motorway congestions and the inability to increase motorway capacity in urban environments requires the implementation of advanced control methods. These methods are an integral part of Intelligent Transportation Systems (ITS). An ITS essentially integrates information and communication technology to solve the congestion problems. Ramp metering (RM) and Variable Speed Limit Control (VSLC) are some of the most widely used urban motorway traffic control methods. RM provide direct influence over the on-ramp flows by using specialized traffic lights, while the VSLC control speed of mainstream flow by using variable messaging signs. A dedicated algorithm for RM or VSLC uses sensory data form an urban motorway to compute actions that will have a positive impact on both types of traffic flow. This study will focus on the cooperation of an RM and a VSLC systems, and the integration of several different RM algorithms into a single algorithm called INTEGRA. The algorithm is created by using the Adaptive Neuro-fuzzy Inference System (ANFIS) as an instance of machine learning techniques. Furthermore, INTGERA is expanded in order to integrate its original functionality with a recurrent neural network for traffic demand prediction. As the final step, this doctoral thesis will provide evaluation of different criteria for learning dataset functional setup, based on which ANFIS neural network of INTEGRA will be learned. Results of all mentioned approaches will be compared and discussed in relation with other commonly used urban motorway control methods.