prikaz prve stranice dokumenta Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala
  Download
PDF 2.75 MB
master's thesis
Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala
Zagreb: University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture, 2019. urn:nbn:hr:235:627069
Gojanović-Rakić, Matej
University of Zagreb
Faculty of Mechanical Engineering and Naval Architecture

Institutional repository: Repository of Faculty of Mechanical Engineering and Naval Architecture University of Zagreb

Cite this document

Gojanović Rakić, M. (2019). Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala (Master's thesis). Zagreb: University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture. Retrieved from https://urn.nsk.hr/urn:nbn:hr:235:627069

Gojanović Rakić, Matej. "Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala." Master's thesis, University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture, 2019. https://urn.nsk.hr/urn:nbn:hr:235:627069

Gojanović Rakić, Matej. "Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala." Master's thesis, University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture, 2019. https://urn.nsk.hr/urn:nbn:hr:235:627069

Gojanović Rakić, M. (2019). 'Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala', Master's thesis, University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture, accessed 19 January 2025, https://urn.nsk.hr/urn:nbn:hr:235:627069

Gojanović Rakić M. Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala [Master's thesis]. Zagreb: University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture; 2019 [cited 2025 January 19] Available at: https://urn.nsk.hr/urn:nbn:hr:235:627069

M. Gojanović Rakić, "Istraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala", Master's thesis, University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:235:627069

Metadata
TitleIstraživanje mogućnosti za uspostavom sposobnosti in vitro ispitivanja bioaktivnosti površina materijala
Title (english)An exploration into possibilities for establishing the ability of in vitro bioactivity testing of materials' surfaces
AuthorMatej Gojanović-Rakić
MentorBožidar Matijević (mentor)
MentorIvan Kumić (mentor)
GranterUniversity of Zagreb
Faculty of Mechanical Engineering and Naval Architecture
Zagreb
Defense date and country2019-07-11, Croatia
Scientific / art field,
discipline and subdiscipline		TECHNICAL SCIENCES
Mechanical Engineering
Abstract
U ovom radu istražen je utjecaj površinskog stanja titanove legure Ti6Al4V ELI na njezinu bioaktivnost u simulirajućoj tjelesnoj tekućini (SBF-u). Nakon izlaganja četiriju uzoraka različitih površinskih stanja SBF-u i analize rezultata, uspoređeno je stanje površine prije i nakon provedenog ispitivanja bioaktivnosti. Ovaj rad podijeljen je na dva dijela; teoretski i eksperimentalni. Teoretski dio sadrži uvod u rad, opis SBF-a, njegove povijesti i vrsta, mehanizma djelovanja, kao i opis nastanka hidroksiapatita. U eksperimentalnom dijelu predočen je postupak istraživanja mogućnosti in vitro ispitivanja bioaktivnosti najčešće korištene titanove legure u medicinskoj primjeni. Pokus se sastojao od pripreme površina titanovih legura, pripreme SBF-a, provedbe ispitivanja bioaktivnosti u dvije iteracije SBF-a te analize stanja površina prije i poslije svakog koraka ispitivanja. Postupak pripreme površina proveden je u Laboratoriju za toplinsku obradu, dok je testiranje bioaktivnosti provedeno u Laboratoriju za analizu metala Fakulteta strojarstva i brodogradnje. Mjerenje parametara hrapavosti provedeno je u Laboratoriju za precizna mjerenja, dok je analiza površina uzoraka svjetlosnom mikroskopijom provedena u Laboratoriju za materijalografiju Fakulteta strojarstva i brodogradnje Sveučilišta u Zagrebu. Nakon provedbe eksperimenta doneseni su odgovarajući zaključci.
Abstract (english)
The influence of the Ti6Al4V ELI titanium alloy’s surface state on its bioactivity in simulated body fluid (SBF) was studied in this paper. After the exposure of four samples of different surface modifications to the SBF and the subsequent analysis of the results, a comparison of the results was carried out. This paper is divided into two parts, the theoretical and the experimental part. The theoretical part contains an introduction to the paper, a description of the SBF, its history, its type and the mechanism of action, as well as the description of hydroxyapatite formation. In the experimental part, a study was carried out to investigate the possibilities for in vitro bioactivity testing. The experiment consisted of the acquisition and initial preparation of titanium alloy surfaces, SBF preparation, bioactivity testing in two SBF iterations and surface condition analysis before and after each test step. The surface preparation process was performed at the Heat Treatment Laboratory, while bioactivity testing was conducted at the Laboratory for Metal Analysis of the Faculty of Mechanical Engineering and Naval Architecture. Measurement of the roughness parameters was performed at the Laboratory for Precise Measurements, while the sample surface analysis by light microscopy was performed in the Laboratory for Materialography of the Faculty of Mechanical Engineering and Naval Architecture of the University of Zagreb. Following the implementation of the experiment, appropriate conclusions were made.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:235:627069
Study programmeTitle: Mechanical Engineering
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka strojarstva (magistar/magistra inženjer/inženjerka strojarstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-07-03 14:07:36