Title GESTACIJSKI DIJABETES MELITUS
Title (english) GESTATIONAL DIABETES MELLITUS
Author Magdalena Branilović
Mentor Natalija Vuletić (mentor)
Committee member Aleks Finderle (predsjednik povjerenstva)
Committee member Natalija Vuletić (član povjerenstva)
Granter University of Rijeka Faculty of Health Studies (Department of Nursing) Rijeka
Defense date and country 2020-09-11, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Gynecology and Obstetrics
Abstract Od prvog poznatog evidentiranog slučaja gestacijskog dijabetesa koji je zabilježen u knjizi »De diabete mellito, graviditatis symptomate« autora Heinricha G. Bennewitza 1824. godine, pa sve do danas istraženi su mnogi aspekti najčešćeg metaboličkog poremećaja u trudnoći. Njegovi komorbiditeti daleko nadilaze u majčino zdravlje i zdravlje potomstva, stoga prevencija gestacijskog dijabetesa mora biti obuhvaćena javno zdravstvenim aktivnostima. Učestalost poremećaja metabolizma ugljikohidrata u trudnoći kontinuirano raste, što govore i brojke da se gestacijski dijabetes javlja u 16 % svih porođaja. Studija koja je inicijalno pokrenuta 2000. godine radi unaprjeđenja dijagnostičkih kriterija koja su utemeljena na ishodima trudnoće dokazala je da i »niže« vrijednosti majčine glikemije imaju značajan utjecaj na ishod trudnoće. Stoga je u većini zdravstvenih sustava došlo do promjena i prihvaćanja novih kriterija koja su razumljivo dovela do povećanja broja slučajeva, ali i smanjenju rizičnih komplikacija povezanih s neliječenjem. Zabrinutost znanstvene zajednice povećava se kao prvo radi utjecaja gestacijskog dijabetesa na već alarmantno povećanje pojavnosti šećerne bolesti te kardiovaskularnih bolesti, a nakon toga radi izostanka jedinstvenog pristupa dijagnostici već nekoliko desetljeća. Samokontrola glikemije, uključivanje fizičke aktivnosti te uravnotežena prehrana primarni su koraci u liječenju. Izostanak normoglikemije promjenom životnog stila indicira uvođenje inzulinske terapije. Inzulin je prvi izbor te je nedavno potvrđena učinkovitost i sigurnost nekih analoga inzulina, poput »inzulina lispro, aspart i detemir«, kao i peroralnih hipoglikemika. Pravilno upravljanje ovim sve češćim poremećajem u trudnoći jedino možemo unaprijediti kliničkim istraživanjima čiji su ciljevi identifikacija genetskih čimbenika, čimbenika rizika te patofizioloških mehanizama.
Abstract (english) From the first known documented case of gestational diabetes recorded in Heinrich G. Bennewitz 's book »De diabete mellito, graviditatis symptomat« in 1824. to the present day, many aspects of the most common metabolic disorder during pregnancy have been explored. It's comorbidities far outweigh mother's wellbeing and offspring's wellbeing, thus the avoidance of gestational diabetes needs to be incorporated in public health programs. The incidence of carbohydrate metabolism disorders in pregnancy is continuously increasing, as evidenced by the figures which show that gestational diabetes occurs in 16 % of all births. A study initially launched in 2000. to improve diagnostic criteria based on pregnancy outcomes proved that even »lower« maternal glycemic values have a significant impact on pregnancy outcome. Therefore, changes and adoption of new criteria have arisen in most health systems and have, understandably, lead to an rise in the number of cases, but also to a decrease in non-treatment-related risk complications. The scientific community 's concern is growing, first because of the impact of gestational diabetes on the already alarming increase in the incidence of diabetes and cardiovascular disease, and then because of the lack of an unified diagnostic approach for several decades. Glycemic self-control, inclusion of physical activity and a balanced diet are the primary steps in treatment. The absence of normoglycemia by lifestyle change indicates the introduction of insulin therapy. Insulin is the first choice and the efficacy and safety of some insulin analogues, such as »insulin lispro, aspart and detemir«, as well as oral hypoglycaemic agents, have recently been confirmed. Proper management of this increasingly common disorder in pregnancy can only be improved by clinical research aimed at identifying genetic factors, risk factors, and pathophysiological mechanisms.
Keywords
gestacijski dijabetes
metabolički poremećaj
komorbiditeti
trudnoća
javno zdravstvene aktivnosti
Keywords (english)
gestational diabetes
metabolic disorder
comorbidities
pregnancy
public health activities
Language croatian
URN:NBN urn:nbn:hr:184:586258
Study programme Title: Professional study of Midwifery (Biomedicine and Healthcare; clinical medical sciences) - Part-time study program Study programme type: professional Study level: undergraduate Academic / professional title: stručni/a prvostupnik / prvostupnica (baccalaureus / baccalaurea) primaljstva (stručni/a prvostupnik / prvostupnica (baccalaureus / baccalaurea) primaljstva)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2021-02-03 09:04:57