Title STATUS VITAMINA D U OSOBA S DEBLJINOM : Diplomski rad Title (english) VITAMIN D STATUS IN PEOPLE WITH OBESITY : Master thesis Author Dorotea Dumenčić Mentor Sanja Klobučar-Majanović (mentor)Committee member Dijana Detel (predsjednik povjerenstva)Committee member Vanja Licul (član povjerenstva)Committee member Tatjana Bogović Crnčić (član povjerenstva)Granter University of Rijeka Defense date and country 2022-06-29, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract Debljina pripada skupini kroničnih nezaraznih bolesti i na globalnoj razini je u konstantnom rastu, a prema Svjetskoj zdravstvenoj organizaciji, 2016. godine, stopa pretilosti u svijetu iznosila 13,1% što je skoro tri puta više nego 1975. godine. Budući da je debljina bolest multifaktorijalnog porijekla pod čime podrazumijevamo demografske, socioekonomske, genetske i bihevioralne čimbenike. S obzirom na to na smanjenje stope debljine možemo utjecati iz više različitih smjerova. Debljina kao bolest ne utječe samo na vanjsku sliku tijela, već ima negativan utjecaj na razne procese koji se odvijaju u našem organizmu, a koji mogu pogodovati razvoju raznih bolesti koje mogu dovesti do smrti. Između ostalog istraživanja pokazuju da je debljina povezana s deficitom vitamina D koji, osim putem hrane, u organizam dospijeva preko kože nakon utjecaja UVB zraka na istu te u našem organizmu ima ulogu u gotovo svim organskim sustavima. Cilj ovog istraživanja bio je dokazati povezanost debljine i deficita vitamina D. U tu svrhu korišteni su podaci antropometrijski, biokemijski podaci i podaci o sastavu tijela 100 nasumično izabranih pretilih ispitanika koji su evidentirani u Ambulanti za debljinu, Kliničkog bolničkog centra Rijeka. Podaci su statistički obrađeni, a dobiveni rezultati pokazali su da 89% ispitanika ima serumsku razinu 25(OH)D nižu od preporučenih 75 nmol/L, a čak 30% ima serumsku razinu 25(OH)D nižu od 30 nmol/L, odnosno u teškom su deficitu. Također, istraživanje je pokazalo kako postoji statistički značajna povezanost između statusa vitamina D i ITM-a, masne mase i nemasne mase pri čemu je korelacija između statusa vitamina D i ITM-a i masne mase negativna, dok je korelacija između statusa vitamina D i nemasne mase pozitivna. Potrebno provesti još istraživanja kojima bi se utvrdio razlog deficita vitamina D kod pretilih osoba, a isto tako, potrebno je kontinuirano provoditi edukaciju populacije o štetnom utjecaju debljine na sve organske sustave te razviti smjernice za povećani unos vitamina D kod pretilih osoba.
Abstract (english) Obesity belongs to the group of chronic non-communicable diseases and is constantly growing globally. According to the World Health Organization, in 2016, the obesity rate in the world was 13.1%, which is almost three times higher than in 1975. Obesity is a disease of multifactorial origin, consisting of demographic, socioeconomic, genetic and behavioral factors. Therefore, we can influence the reduction of obesity rate from several different directions. Obesity as a disease not only affects the external image of the body, but also has a negative impact on various processes that take place in our body, which can favor the development of various diseases that can lead to death. Research projects show that obesity is, among other things, associated with vitamin D deficiency. Vitamin D enters the body through food intake but also through the skin after exposure to UVB rays, and in our body has a role in almost all organ systems. The aim of this study was to prove the relationship between obesity and vitamin D deficiency. For this purpose, anthropometric, biochemical and body composition data of 100 randomly selected obese subjects were registered in the Obesity Clinic, Clinical Hospital Center Rijeka. That data was statistically processed, and the obtained results showed that 89% of respondents have a serum level of 25 (OH) D lower than the recommended 75 nmol/L, and as many as 30% have a serum level of 25 (OH) D lower than 30 nmol/L which means that they are in a severe deficit. Also, research has shown that there is a statistically significant association between vitamin D status and BMI, fat mass and lean mass with a correlation between vitamin D status and BMI and fat mass is negative, while the correlation between vitamin D status and lean mass is positive. Additional research is needed to determine the cause of vitamin D deficiency in obese people while continuously educating the population about the harmful effects of obesity on all organ systems. In addition, guidelines for increased vitamin D intake in obese individuals need to be developed.
Keywords
pretilost
debljina
vitamin D
25(OH)D
indeks tjelesne mase
Keywords (english)
obesity
overweight
vitamin D
25(OH)D
body mass index
Language croatian URN:NBN urn:nbn:hr:184:187286 Study programme Title: Graduate university Study of Clinical Nutrition Type of resource Text File origin Born digital Access conditions Open access Terms of use Created on 2022-06-17 18:59:46
