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undergraduate thesis
Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije
Rijeka: University of Rijeka, Faculty of Health Studies, 2022. urn:nbn:hr:184:922533
Karić, Elma
University of Rijeka
Faculty of Health Studies
Department of Laboratory and Radiological Diagnostics

Institutional repository: Repository of the University of Rijeka, Faculty of Health Studies

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Karić, E. (2022). Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije (Undergraduate thesis). Rijeka: University of Rijeka, Faculty of Health Studies. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:922533

Karić, Elma. "Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije." Undergraduate thesis, University of Rijeka, Faculty of Health Studies, 2022. https://urn.nsk.hr/urn:nbn:hr:184:922533

Karić, Elma. "Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije." Undergraduate thesis, University of Rijeka, Faculty of Health Studies, 2022. https://urn.nsk.hr/urn:nbn:hr:184:922533

Karić, E. (2022). 'Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije', Undergraduate thesis, University of Rijeka, Faculty of Health Studies, accessed 06 May 2024, https://urn.nsk.hr/urn:nbn:hr:184:922533

Karić E. Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije [Undergraduate thesis]. Rijeka: University of Rijeka, Faculty of Health Studies; 2022 [cited 2024 May 06] Available at: https://urn.nsk.hr/urn:nbn:hr:184:922533

E. Karić, "Perfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije", Undergraduate thesis, University of Rijeka, Faculty of Health Studies, Rijeka, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:184:922533

Metadata
TitlePerfuzijska tomografija miokarda s farmakološkim opterećenjem tijekom COVID-19 pandemije
Title (english)Myocardial perfusion tomography with pharmacological stress testing in the COVID-19 pandemic
AuthorElma Karić
MentorNeva Girotto (mentor)
MentorTatjana Bogović Crnčić (komentor)
Committee memberSvjetlana Grbac-Ivanković (predsjednik povjerenstva)
Committee memberHana Mahmutefendić Lučin (član povjerenstva)
Committee memberSanja Klobučar-Majanović (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Health Studies
(Department of Laboratory and Radiological Diagnostics)
Rijeka
Defense date and country2022-07-18, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Nuclear Medicine
Abstract
Perfuzijska tomografija miokarda je neinvazivna slikovna dijagnostička metoda u nuklearnoj medicini koja se izvodi u svrhu procjenu raspodjele koronarnog protoka u srčanom mišiću. Pretraga se izvodi intravenskim injiciranjem radiofarmaka - 99mTc-MIBI-ja ili 99mTc-tetrofosmina koji se nakupljaju u miokardu proporcionalno protoku krvi te se zasebno apliciraju u opterećenju i mirovanju pa se snimke dobivene gama kamerom međusobno uspoređuju. Opterećenje se, osim bicikl ergometrom ili pokretnom trakom, može u slučaju određenih indikacija izvoditi lijekovima – najčešće vazodilatatorima koji povećavaju protok krvi kroz srčani mišić. Tijekom COVID-19 pandemije objavljene su preporuke strukovnih udruženja nuklearne medicine, prema kojima bi, iz epidemioloških razloga, pretragu trebalo izvoditi farmakološkim opterećenjem i uz jednodnevni protokol. Ciljevi ovog istraživanja su ustanoviti postiže li se jednodnevnim protokolom s regadenozonom adekvatno opterećenje, utvrditi jesu li registrirane nuspojave regadenozona i koje te ustanoviti jesu li snimke snimljene jednodnevnim protokolom zadovoljavajuće kvalitete. U istraživanje je uključeno 50 ispitanika upućenih u Klinički zavod za nuklearnu medicinu Kliničkog bolničkog centra Rijeka na perfuzijsku tomografiju miokarda uz farmakološko opterećenje vazodilatatorom regadenozonom prema jednodnevnom protokolu, tijekom 2020. i 2021. godine. Podaci koji su analizirani su dob, spol, uputna dijagnoza, nuspojave farmakološkog opterećenja, kvaliteta snimljenih tomograma te konačan nalaz. Zaključeno je da su sve snimke učinjene farmakološkim opterećenjem zadovoljavajuće kvalitete za interpretaciju kao i da se regadenozonom može postići adekvatno opterećenje. Također, ustanovljeno je da regadenozon uzrokuje blage nuspojave, u manjem postotku pacijenata.
Abstract (english)
Myocardial perfusion tomography (MPI) is non-invasive nuclear medicine imaging diagnostic method performed to assess the distribution of coronary flow in the heart muscle. The test is performed by intravenous injection of radiopharmaceuticals that accumulate in the myocardium in proportion to blood flow, such as 99mTc- MIBI and 99mTc- tetrofosmin, which are applied separately in stress and rest, and images are compared. Stress imaging is performed with cycloergometer or treadmill, but in some indications pharmacological stressors can be used, mostly vasodilators that increase blood flow through the heart muscle. During COVID19 pandemic, nuclear medicine associations have published recommendations according to which, for epidemiological reasons, MPI should be performed as one-day protocol and with pharmacological stress. The objectives of this study were to determine whether by using one-day protocol with regadenoson an adequate stress can be achieved, whether and which regadenoson side effects have been registered, and to determine whether quality of images obtained with one day protocol was satisfactory. The study included 50 subjects referred to Clinical Department of Nuclear Medicine, Clinical Hospital Center Rijeka, during 2020 and 2021. for myocardial perfusion tomography with regadenoson pharmacological stress with one-day protocol. The data analysed were age, sex, referral diagnosis, pharmacological stress side effects, tomogram quality and final findings. It was concluded that all images made with a pharmacological stress are of satisfactory quality for interpretation, as well as that an adequate stress can be achieved with regadenoson. Also, regadenoson has been found to cause only mild side effects, in a smaller proportion of patients.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:922533
Study programmeTitle: Radiological Technology
Study programme type: professional
Study level: undergraduate
Academic / professional title: stručni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) radiološke tehnologije (stručni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) radiološke tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2022-07-06 16:54:23