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master's thesis
PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem
Rijeka: University of Rijeka, Faculty of Health Studies, 2023. urn:nbn:hr:184:530781
Franjković, Kristina
University of Rijeka
Faculty of Health Studies

Institutional repository: Repository of the University of Rijeka, Faculty of Health Studies

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Franjković, K. (2023). PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem (Master's thesis). Rijeka: University of Rijeka, Faculty of Health Studies. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:530781

Franjković, Kristina. "PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem." Master's thesis, University of Rijeka, Faculty of Health Studies, 2023. https://urn.nsk.hr/urn:nbn:hr:184:530781

Franjković, Kristina. "PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem." Master's thesis, University of Rijeka, Faculty of Health Studies, 2023. https://urn.nsk.hr/urn:nbn:hr:184:530781

Franjković, K. (2023). 'PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem', Master's thesis, University of Rijeka, Faculty of Health Studies, accessed 06 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:530781

Franjković K. PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem [Master's thesis]. Rijeka: University of Rijeka, Faculty of Health Studies; 2023 [cited 2024 November 06] Available at: https://urn.nsk.hr/urn:nbn:hr:184:530781

K. Franjković, "PRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem", Master's thesis, University of Rijeka, Faculty of Health Studies, Rijeka, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:184:530781

Metadata
TitlePRIMJENA TRANEKSAMIČNE KISELINE KOD UGRADNJE TOTALNE ENDOPROTEZE KUKA: rad s istraživanjem
Title (english)APPLICATION OF TRANEXAMIC ACID IN TOTAL HIP ARTHROPLASTY: research
AuthorKristina Franjković
MentorNikola Gržalja (mentor)
Committee memberVeljko Šantić (predsjednik povjerenstva)
Committee memberDalen Legović (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Health Studies
Rijeka
Defense date and country2023-09-29, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Orthopedics
Abstract
Cilj istraživanja: Ugradnja totalne endoproteze kuka jedan je od najčešće izvođenih zahvata u ortopediji i traumatologiji. Iako je ugradnja totalne endoproteze kuka danas rutinski i siguran zahvat, može biti povezana s povećanim perioperacijskim krvarenjem koje može dovesti do komplikacija i produljene hospitalizacije bolesnika. U zadnjem desetljeću u ortopediji i traumatologiji primjenjuje se traneksamična kiselina s ciljem smanjivanja unutar- i poslijeoperacijskog krvarenja. Cilj ovog istraživanja bio je utvrditi postoji li razlika u krvarenju i potrebi za primjenom tranfuzijskih pripravaka između skupine bolesnika koji su primili traneksamičnu kiselinu i skupine bolesnika koji nisu primili traneksamičnu kiselinu u preoperativnom periodu. Ispitanici i metode: U ovo retrospektivno istraživanje bilo je uključeno osamdeset bolesnika kod kojih je učinjena ugradnja totalne endoproteze kuka u radoblju od 1.07.2022. do 1.01.2023. godine. Od uključenih osamdeset bolesnika četrdeset je primilo traneksamičnu kiselinu, a četrdeset bolesnika nije primilo transeksamičnu kiselinu u preoperativnom razdoblju. Rezultati: Količina intraoperativnog krvarenja kod bolesnika koji su primili traneksamičnu kiselinu bila je manja od količine intraoperativnog krvarenja kod bolesnika koji nisu primili traneksamičnu kiselinu, no ista nije bila statistički značajna. U skupini bolesnika koji su primili traneksamičnu kiselinu bila je statistički značajna manja potreba za primjenom transfuzije krvi u ranom poslijeoperacijskom razdoblju. Zaključak: Iz dobivenih rezultata može se zaključiti da preoperativna primjena traneksamične kiseline smanjuje potrebu za primjenom transfuzije krvi u bolesnika kod ugradnje totalne endoproteze kuka.
Abstract (english)
Objectives: Total hip arthroplasty is one of the most frequently performed procedures in orthopedics and traumatology. Although total hip arthroplasty is today a routine and safe procedure, it can be associated with increased perioperative bleeding that can lead to complications and prolonged hospitalization of the patient. In the last decade, tranexamic acid has been used in orthopedics and traumatology with the aim of reducing intra- and postoperative bleeding. The aim of this study was to determine whether there is a difference in bleeding and the need for blood transfusion between the group of patients who received tranexamic acid and the group of patients who did not receive tranexamic acid in the preoperative period. Patients and methods: In this retrospective study, eighty patients were included in whom total hip endoprosthesis was implanted during the period from 1.07.2022. to 1.01.2023. Of the eighty patients included, forty received tranexamic acid, and forty patients did not receive transexamic acid in the preoperative period. Results: The amount of intraoperative bleeding in patients who received tranexamic acid was less than the amount of intraoperative bleeding in patients who did not receive tranexamic acid, but it was not statistically significant. In the group of patients who received tranexamic acid, there was a statistically significant reduced need for blood transfusion. Conclusion: From the obtained results, it can be concluded that preoperative administration of tranexamic acid reduces the need for blood transfusion in patients undergoing total hip arthroplasty.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:530781
Study programmeTitle: Graduate university study of Nursing: Healthcare Management (Biomedicine and Healthcare; clinical medical sciences)
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-09-20 11:34:14