prikaz prve stranice dokumenta Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings
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Scientific paper - Original scientific paper
Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings
International Journal of Infectious Diseases, 137 (2023); 98-110. https://doi.org/10.1016/j.ijid.2023.10.013
Rossi, Giuseppe; Salmanton-García, Jon; Cattaneo, Chiara; Marchesi, Francesco; Dávila-Valls, Julio; Martín-Pérez, Sonia; Itri, Federico; López-García, Alberto; Glenthøj, Andreas; Gomes da Silva, Maria; Besson, Caroline; Marchetti, Monia; Weinbergerová, Barbora; Jaksic, Ozren; Jiménez, Moraima; Bilgin, Yavuz M.; Van Doesum, Jaap; Farina, Francesca; Žák, Pavel; Verga, Luisa; Collins, Graham P.; Bonuomo, Valentina; Van Praet, Jens; Nucci, Marcio; Meers, Stef; Espigado, Ildefonso; Fracchiolla, Nicola S.; Valković, Toni; Poulsen, Christian Bjørn; Čolović, Natasha; Dragonetti, Giulia; Ledoux, Marie-Pierre; Tascini, Carlo; Buquicchio, Caterina; Blennow, Ola; Passamonti, Francesco; Machado, Marina; Labrador, Jorge; Duarte, Rafael F.; Schönlein, Martin; Prezioso, Lucia; Falces-Romero, Iker; Kulasekararaj, Austin; Garcia-Vidal, Carolina; Fernández, Noemí; Abu-Zeinah, Ghaith; Ormazabal-Vélez, Irati; Adžić-Vukičević, Tatjana; Piukovics, Klára; Stoma, Igor; Cuccaro, Annarosa; Magliano, Gabriele; Szotkowski, Tomáš; González-López, Tomás-José; El-Ashwah, Shaimaa; Bergantim, Rui; Sili, Uluhan; Maertens, Johan; Demirkan, Fatih; De Ramón, Cristina; Petzer, Verena; Del Principe, Maria Ilaria; Navrátil, Milan; Dargenio, Michelina; Seval, Guldane Cengiz; Samarkos, Michail; Ráčil, Zdeněk; Pinczés, László Imre; Lahmer, Tobias; Busca, Alessandro; Méndez, Gustavo-Adolfo; Vena, Antonio; Biernat, Monika M.; Merelli, Maria; Calbacho, Maria; Barać, Aleksandra; Bavastro, Martina; Limongelli, Alessandro; Ilhan, Osman; Wolf, Dominik; Çolak, Gökçe Melis; García-Sanz, Ramón; Emarah, Ziad; Mišković, Bojana; Gräfe, Stefanie K.; Mladenović, Miloš; Aiello, Tommaso Francesco; Núñez-Martín-Buitrago, Lucía; Nordlander, Anna; Arellano, Elena; Zambrotta, Giovanni Paolo Maria; Ammatuna, Emanuele; Cabirta, Alba; Sacchi, Maria Vittoria; Nunes Rodrigues, Raquel; Hersby, Ditte Stampe; Hanakova, Michaela; Rahimli, Laman; Cordoba, Raul; Cornely, Oliver A.; Pagano, Livio More authors...

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Rossi, G., Salmanton García, J., Cattaneo, C., Marchesi, F., Dávila Valls, J., Martín Pérez, S. ... Pagano, L. (2023). Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings. International Journal of Infectious Diseases, 137., 98-110. doi: 10.1016/j.ijid.2023.10.013

Rossi, Giuseppe, et al. "Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings." International Journal of Infectious Diseases, vol. 137, 2023, pp. 98-110. https://doi.org/10.1016/j.ijid.2023.10.013

Rossi, Giuseppe, Jon Salmanton García, Chiara Cattaneo, Francesco Marchesi, Julio Dávila Valls, Sonia Martín Pérez, Federico Itri, et al. "Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings." International Journal of Infectious Diseases 137 (2023): 98-110. https://doi.org/10.1016/j.ijid.2023.10.013

Rossi, G., et al. (2023) 'Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings', International Journal of Infectious Diseases, 137, pp. 98-110. doi: 10.1016/j.ijid.2023.10.013

Rossi G, Salmanton García J, Cattaneo C, Marchesi F, Dávila Valls J, Martín Pérez S, and sur.. Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings. International Journal of Infectious Diseases [Internet]. 2023 December [cited 2024 November 08];137:98-110. doi: 10.1016/j.ijid.2023.10.013

G. Rossi, et al., "Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings", International Journal of Infectious Diseases, vol. 137, pp. 98-110, December 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:069393. [Accessed: 08 November 2024]

Metadata
Title (english)Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings
AuthorGiuseppe Rossi
AuthorJon Salmanton-García
AuthorChiara Cattaneo
AuthorFrancesco Marchesi
AuthorJulio Dávila-Valls
AuthorSonia Martín-Pérez
AuthorFederico Itri
AuthorAlberto López-García
AuthorAndreas Glenthøj
AuthorMaria Gomes da Silva
AuthorCaroline Besson
AuthorMonia Marchetti
AuthorBarbora Weinbergerová
AuthorOzren Jaksic
AuthorMoraima Jiménez
AuthorYavuz M. Bilgin
AuthorJaap Van Doesum
AuthorFrancesca Farina
AuthorPavel Žák
AuthorLuisa Verga
AuthorGraham P. Collins
AuthorValentina Bonuomo
AuthorJens Van Praet
AuthorMarcio Nucci
AuthorStef Meers
AuthorIldefonso Espigado
AuthorNicola S. Fracchiolla
AuthorToni Valković
AuthorChristian Bjørn Poulsen
AuthorNatasha Čolović
AuthorGiulia Dragonetti
AuthorMarie-Pierre Ledoux
AuthorCarlo Tascini
AuthorCaterina Buquicchio
AuthorOla Blennow
AuthorFrancesco Passamonti
AuthorMarina Machado
AuthorJorge Labrador
AuthorRafael F. Duarte
AuthorMartin Schönlein
AuthorLucia Prezioso
AuthorIker Falces-Romero
AuthorAustin Kulasekararaj
AuthorCarolina Garcia-Vidal
AuthorNoemí Fernández
AuthorGhaith Abu-Zeinah
AuthorIrati Ormazabal-Vélez
AuthorTatjana Adžić-Vukičević
AuthorKlára Piukovics
AuthorIgor Stoma
AuthorAnnarosa Cuccaro
AuthorGabriele Magliano
AuthorTomáš Szotkowski
AuthorTomás-José González-López
AuthorShaimaa El-Ashwah
AuthorRui Bergantim
AuthorUluhan Sili
AuthorJohan Maertens
AuthorFatih Demirkan
AuthorCristina De Ramón
AuthorVerena Petzer
AuthorMaria Ilaria Del Principe
AuthorMilan Navrátil
AuthorMichelina Dargenio
AuthorGuldane Cengiz Seval
AuthorMichail Samarkos
AuthorZdeněk Ráčil
AuthorLászló Imre Pinczés
AuthorTobias Lahmer
AuthorAlessandro Busca
AuthorGustavo-Adolfo Méndez
AuthorAntonio Vena
AuthorMonika M. Biernat
AuthorMaria Merelli
AuthorMaria Calbacho
AuthorAleksandra Barać
AuthorMartina Bavastro
AuthorAlessandro Limongelli
AuthorOsman Ilhan
AuthorDominik Wolf
AuthorGökçe Melis Çolak
AuthorRamón García-Sanz
AuthorZiad Emarah
AuthorBojana Mišković
AuthorStefanie K. Gräfe
AuthorMiloš Mladenović
AuthorTommaso Francesco Aiello
AuthorLucía Núñez-Martín-Buitrago
AuthorAnna Nordlander
AuthorElena Arellano
AuthorGiovanni Paolo Maria Zambrotta
AuthorEmanuele Ammatuna
AuthorAlba Cabirta
AuthorMaria Vittoria Sacchi
AuthorRaquel Nunes Rodrigues
AuthorDitte Stampe Hersby
AuthorMichaela Hanakova
AuthorLaman Rahimli
AuthorRaul Cordoba
AuthorOliver A. Cornely
AuthorLivio Pagano
Author's institutionUniversity of Rijeka
Faculty of Health Studies
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Objectives: Elderly patients with hematologic malignancies face the highest risk of severe COVID-19 outcomes. The infection's impact on different age groups remains unstudied in detail. Methods: We analyzed elderly patients (age groups: 65-70, 71-75, 76-80, and >80 years old) with hematologic malignancies included in the EPICOVIDEHA registry between January 2020 and July 2022. Univariable and multivariable Cox regression models were conducted to identify factors influencing death in COVID-19 patients with hematological malignancy. Results: The study included data from 3,603 elderly patients (aged 65 or older) with hematological malignancy, with a majority being male (58.1%) and a significant proportion having comorbidities. The patients were divided into four age groups, and the analysis assessed COVID-19 outcomes, vaccination status, and other variables in relation to age and pandemic waves. The 90-day survival rate for patients with COVID-19 was 71.2%, with significant differences between groups. The pandemic waves had varying impacts, with the first wave affecting patients over 80 years old, the second being more severe in 65-70, and the third being the least severe in all age groups. Factors contributing to 90-day mortality included age, comorbidities, lymphopenia, active malignancy, acute leukemia, less than three vaccine doses, severe COVID-19, and using only corticosteroids as treatment. Conclusion: These data underscore the heterogeneity of elderly hematological patients, highlight the different impacts of COVID-19 waves and the pivotal importance of vaccination, and may help in planning future healthcare efforts.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Infectious Diseases
Numberingvol. 137, pp. 98-110
p-ISSN1201-9712
DOIhttps://doi.org/10.1016/j.ijid.2023.10.013
URN:NBNurn:nbn:hr:184:069393
Publication2023-12
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S120197122300749X
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-02-26 09:30:31