| Abstract | Uvod: Kardiovaskularne bolesti (KVB) glavni su uzrok invaliditeta i prerane smrti diljem svijeta. Temeljna patologija je ateroskleroza koja se razvija godinama dok se ne pojave prvi simptomi. Perkutana koronarna intervencija (PCI) je postupak ne-kirurške revaskularizacije miokarda i najčešći je invazivni način liječenja ove bolesti. Na brzinu progresije ateroskleroze utječu čimbenici rizika koje dijelimo na promjenjive i nepromjenjive. One na koje možemo utjecati su pušenje, prekomjerna tjelesna masa udružena s neaktivnošću mjereno indeksom tjelesne mase (ITM), arterijska hipertenzija, šećerna bolest i hiperlipidemija. Na spol, dob, obiteljsku predispoziciju i rasu ne možemo utjecati te stoga te čimbenike nazivamo ne promjenjivim.
Cilj istraživanja: Analizirati prisutnost čimbenika rizika u ispitanika liječenih perkutanom koronarnom intervencijom zbog STEMI-ja ili NSTEMI-ja.
Materijali i metode: Ovo retrospektivno istraživanje provelo se na Klinici za bolesti srca i krvnih žila, Kliničkog bolničkog centra Rijeka u razdoblju od 1.6.2023. do 31.12.2023. Obuhvatilo je 302 ispitanika koji su zaprimljeni pod dijagnozom STEMI-ja (šifra I21.-, Međunarodna klasifikacija bolesti (MKB), 10. revizija) kod kojih je učinjena primarna perkutana koronarna intervencija (PCI) i ispitanici s dijagnozom NSTEMI-ja (šifra I21.4 Međunarodna klasifikacija bolesti (MKB) 10. revizija) kod kojih je također učinjena PCI.
Rezultati: Statistički značajna razlika se pojavila u pojedinoj skupini u spolu, u razini GUK-a, vrijednosti arterijskog tlaka, visini pulsa pri prijemu i pri otpustu. Između skupina postoji statistički značajna razlika u podacima o prethodno obavljenim PCI-jima, HDL-kolesterolu, GUK-u pri prijemu i pri otpustu, obiteljskoj anamnezi, trajanju ukupne hospitalizacije i boravku u ZIKL-u, visini hs-TNT-a pri prijemu i njegovim maksimalnim vrijednostima, Killip klasifikaciji, LVEF-u i hospitalnom mortalitetu.
Zaključak: U skupinama ispitanika sa STEMI-jem i NSTEMI-jem koji su liječeni primarnom koronarnom intervencijom nije postojala statistički značajna razlika u spolu, dobi, ITM-u, prisutnosti arterijske hipertenzije, hiperlipidemiji, pušenju, ali je skupina sa STEMI-jem imala statistički značajno višu razinu GUK-a pri prijemu i pri otpustu. |
| Abstract (english) | Introduction: Cardiovascular diseases (CVD) are a major cause of disability and premature death worldwide. The underlying pathology is atherosclerosis, which develops over years until the first symptoms appear. Percutaneous coronary intervention (PCI) is a procedure of non-surgical revascularization of the myocardium and is the most common invasive method of treating this disease. The speed of progression of atherosclerosis is influenced by risk factors that are divided into variable and non-variable. Those that we can influence are smoking, excessive body mass associated with inactivity as measured by body mass index (BMI), arterial hypertension, diabetes and hyperlipidemia. We cannot influence gender, age, family predisposition and race and therefore we call these factors non-changeable.
Research objective: To analyze the presence of risk factors in subjects treated with percutaneous coronary intervention due to STEMI or NSTEMI.
Materials and methods: This retrospective study was conducted at the Clinic for Cardiovascular Diseases, Rijeka Clinical Hospital Center in the period from June 1st, 2023 until December 31st, 2023. It included 302 subjects who were admitted with a diagnosis of STEMI (code I21.-, International Classification of Diseases (ICD), 10th revision) who underwent primary percutaneous coronary intervention (PCI) and subjects with a diagnosis of NSTEMI (code I21.4 International classification of diseases (ICD) 10th revision) in which was also performed PCI.
Results: A statistically significant difference appeared in each group in gender, BGL, arterial pressure value, pulse rate at admission and at discharge. There is a statistically significant difference between the groups in the data on previously performed PCI, HDL-cholesterol, BGL at admission and at discharge, family history, duration of total hospitalization and stay in ZIKL, hs-TNT level at admission and maximum values, Killip classification, LVEF, hospital mortality.
Conclusion: In the groups of subjects with STEMI and NSTEMI who were treated with primary coronary intervention, there was no statistically significant difference in gender, age, BMI, presence of arterial hypertension, hyperlipidemia, smoking, but the group with STEMI had a statistically significant higher BGL at admission and at discharge. |
